arXiv AI

Hypnos: Learning Generalisable Representations of Sleep Physiology via Next-Token Prediction

Hypnos is a multi‑modal sleep foundation model that learns generalisable representations of physiological signals by predicting the next token across eight sensing modalities (EEG, ECG, respiratory, etc.) using an auto‑regressive RQ‑Transformer. Trained on over 20,000 overnight polysomnography recordings, it outperforms existing foundation models on most benchmarks, matching strong supervised baselines for sleep‑stage classification while requiring 100× less labelled data. Additionally, Hypnos generalises beyond sleep, surpassing a dedicated ECG model in atrial fibrillation detection.

arXiv AI
Jul 13

Omni-Sleep: A Sleep Foundation Model via Hierarchical Contrastive Learning of CNS-ANS Dynamics

arXiv:2607. 07720v2 Announce Type: replace-cross Abstract: Sleep physiology arises from the coordinated dynamics of the central nervous system (CNS) and autonomic nervous system (ANS), as reflected by multimodal polysomnography signals including EEG, EOG, EMG, ECG, and respiration.

By Zhoujie Hou, Song Wang, Kexin Lou, Mo Wang, Chen Wei, Quanying Liu
arXiv Machine Learning
Aug 14

CardioState-JEPA: Delay-Aware Cross-Modal Learning of a Shared Cardiac Representation

arXiv:2608. 12944v1 Announce Type: new Abstract: Electrocardiography (ECG), photoplethysmography (PPG), and phonocardiography (PCG) provide complementary views of the same cardiac cycle, yet existing cardiac foundation models are trained for a single sensing modality, leaving the shared physiology across sensors unexploited.

By Hamza Shafiq, Hung Manh Pham, Bin Zhu, Pan Zhou, Jun Hu, Aaqib Saeed
arXiv AI
Jun 2

Towards a General Intelligence and Interface for Wearable Health Data

arXiv:2605. 22759v2 Announce Type: replace Abstract: While ubiquitous wearable sensors capture a wealth of behavioral and physiological information, effectively transforming these signals into personalized health insights is challenging.

By Girish Narayanswamy, Maxwell A. Xu, A. Ali Heydari, Samy Abdel-Ghaffar, Marius Guerard, Kara Vaillancourt, Zhihan Zhang, Jake Garrison, Levi Albuquerque, Dimitris Spathis, Hong Yu, Hamid Palangi, Xuhai "Orson" Xu, David G. T. Barrett, Joseph Breda, Jed McGiffin, Yubin Kim, Yuwei Zhang, Naghmeh Rezaei, Samuel Solomon, Karan Ahuja, Tim Althoff, Jake Sunshine, Ming-Zher Poh, Benjamin Yetton, Ari Winbush, Nicholas B. Allen, James M. Rehg, Isaac Galatzer-Levy, Yun Liu, John Hernandez, Anupam Pathak, Conor Heneghan, Yuzhe Yang, Ahmed A. Metwally, Pushmeet Kohli, Mark Malhotra, Shwetak Patel, Xin Liu, Daniel McDuff
arXiv AI
Sep 21

BEAT-Net: Injecting Biomimetic Spatio-Temporal Priors for Interpretable ECG Diagnosis

BEAT-Net is a supervised biomimetic framework for ECG diagnosis that incorporates QRS-centered tokenization and a hierarchical architecture mirroring a cardiologist’s workflow. It processes heartbeat sequences through morphological, spatial, temporal, and transformer-based stages, achieving an AUC of 0.924 on large benchmarks while using only 0.7 million parameters. The model outperforms the 39.5‑million‑parameter HeartLang foundation model on morphological form classification and demonstrates superior cross‑dataset generalization with only 35% of the training data.

By Runze Ma, Haonan Lyu, Shunbo Jia, Qiang Yang, Muzi Xu, Jiaqi Zhang, Zihe Luo, Caizhi Liao