arXiv:2508. 03750v2 Announce Type: replace Abstract: Early and accurate glaucoma detection is critical to prevent irreversible vision loss, yet existing AI methods often rely on unimodal inputs and lack interpretability.
By Cheng Huang, Zeyu Han, Weizheng Xie, Karanjit Kooner, Tsengdar Lee, Jui-Kai Wang, Jia Zhang
arXiv:2603. 07131v4 Announce Type: replace-cross Abstract: Large Vision Language Models (LVLMs) show immense potential for automated ophthalmic diagnosis.
By Shuai Lu, Meng Wang, Jia Guo, Jiawei Du, Bo Liu, Shengzhu Yang, Weihang Zhang, Huazhu Fu, Huiqi Li
arXiv:2607. 09664v1 Announce Type: new Abstract: To provide a structured and interpretable assessment, we decompose the image-based diagnosis into components following the Toulmin model of argumentation.
By Anca Marginean, Adrian Groza
arXiv:2608. 09752v1 Announce Type: cross Abstract: Retinal fundus images frequently exhibit multiple co-occurring pathologies, yet standard deep learning classifiers apply static, identical computation to every image regardless of the underlying disease distribution.
By Nagur Shareef Shaik, Jeongwoo Park, Yeong-Jin Kim, Jaeuk Jung, Hyunjung Oh, Dong Hye Ye
arXiv:2607. 21068v1 Announce Type: new Abstract: Automated detection of vision impairing retina-based ocular conditions from fundus images is important for early screening, timely referral and reducing dependency on specialist-only assessment, for which neural network-based deep learning (DL) models have been widely utilized.
By Kritanu Chattopadhyay, Sayanjit Singha Roy, Soumya Chatterjee
arXiv:2606. 12169v1 Announce Type: cross Abstract: High-stakes clinical use of large vision-language models (LVLMs) requires reasoning that is grounded in visual evidence and clinical knowledge, not just correct final answers.
By Negin Baghbanzadeh, Pritam Sarkar, Michael Colacci, Abeer Badawi, Adibvafa Fallahpour, Arash Afkanpour, Leonid Sigal, Ali Etemad, Elham Dolatabadi
arXiv:2606. 18063v1 Announce Type: cross Abstract: Medical image classification faces a fundamental dilemma: while deep learning models achieve remarkable performance at scale, real-world clinical scenarios often suffer from severe data scarcity due to annotation costs, privacy constraints, and disease rarity.
By Ruman Wang, Hangting Ye
arXiv:2608. 07651v1 Announce Type: new Abstract: Large language models (LLMs) show promise in medical image interpretation but suffer from hallucination, limited accuracy, and run-to-run inconsistency.
By Jalil Jalili, Hossein Taghizad, Anuwat Jiravarnsirikul, Christopher Bowd, Akram Belghith, Raheleh Kafieh, Christopher A. Girkin, Sally L. Baxter, Robert N. Weinreb, Linda M. Zangwill, Mark Christopher
arXiv:2607. 28538v1 Announce Type: cross Abstract: Classifying pathological scars from clinical photographs requires distinguishing keloids from hypertrophic scars despite limited expert-labeled data and substantial acquisition variation across hospitals.
By Ruman Wang, Hangting Ye
arXiv:2607. 25324v1 Announce Type: cross Abstract: Glaucoma is a group of eye diseases that damage the optic nerve, often caused by elevated intraocular pressure.
By Sai Venkatesh Chilukoti, Krishna Rauniyar, Min Shi, Xiali Hei
arXiv:2606. 06224v1 Announce Type: cross Abstract: Explanations of multiple instance learning (MIL) models are widely used for validation and discovery in digital histopathology.
By Yanqing Luo (Berlin Institute for the Foundations of Learning and Data, Berlin, Germany, Machine Learning Group, Technische Universit\"at Berlin, Berlin, Germany), Julius Hense (Berlin Institute for the Foundations of Learning and Data, Berlin, Germany, Machine Learning Group, Technische Universit\"at Berlin, Berlin, Germany), Niklas Preni{\ss}l (Institute of Pathology, Charit\'e Universit\"atsmedizin, Berlin, Germany, Berlin Institute of Health at Charit\'e -- Universit\"atsmedizin Berlin, BIH Biomedical Innovation Academy, BIH Charit\'e Digital Clinician Scientist Program, Berlin, Germany), Andreas Mock (Institute of Pathology, Ludwig Maximilian University of Munich, Munich, Germany, Division of Translational Medical Oncology, DKFZ, Heidelberg, Germany, NCT Heidelberg, Heidelberg, Germany, German Cancer Consortium), Klaus-Robert M\"uller (Berlin Institute for the Foundations of Learning and Data, Berlin, Germany, Machine Learning Group, Technische Universit\"at Berlin, Berlin, Germany, Department of Artificial Intelligence, Korea University, Seoul, Korea, Max-Planck Institute for Informatics, Saarbr\"ucken, Germany), Thomas Schnake (Department of Chemistry, Chemical Physics Theory Group, University of Toronto, Canada, Vector Institute for Artificial Intelligence, Toronto, Canada, Acceleration Consortium, University of Toronto, Canada), Mina Jamshidi Idaji (Berlin Institute for the Foundations of Learning and Data, Berlin, Germany, Machine Learning Group, Technische Universit\"at Berlin, Berlin, Germany)
Automated diabetic retinopathy (DR) grading from colour fundus photographs can achieve strong predictive performance, but clinical interpretation requires more than an image-level label. It requires understanding how lesion evidence is distributed around retinal vessels and how this evidence relates to quantitative vascular biomarkers.