OpenAI Blog
May 29
Boston Children’s uses AI to unlock new diagnoses
Boston Children’s Hospital uses OpenAI technology to improve patient care, reduce operational burden, and help diagnose more than 40 rare disease cases.
Using AI to help physicians diagnose rare genetic diseases affecting children
Researchers used an OpenAI reasoning model to help diagnose rare diseases, identifying 18 new diagnoses in previously unsolved cases.
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OpenAI Blog
Sep 12, 2024
Decoding genetics with OpenAI o1
Geneticist Catherine Brownstein demonstrates how OpenAI o1 can speed up the process of diagnosing rare medical challenges.
arXiv AI
Jun 16
LiteOdyssey: A Lightweight Reasoning AI Agent for Interpretable Rare-Disease Diagnosis
arXiv:2606. 16149v1 Announce Type: new Abstract: Most medical AI systems improve by scaling additional machinery: more fine-tuning data, more agents, and/or larger retrieval databases.
OpenAI Blog
Mar 6, 2024
Using AI to improve patient access to clinical trials
Paradigm uses OpenAI’s API to improve patient access to clinical trials.
arXiv AI
Jun 24
A specialized reasoning large language model for accelerating rare disease diagnosis: a randomized AI physician assistance trial
arXiv:2606. 24510v1 Announce Type: new Abstract: Rare diseases affect millions of individuals worldwide, yet timely diagnosis remains a major public health challenge due to scarcity of specialized clinical expertise.
OpenAI Blog
Jan 8
OpenAI for Healthcare
OpenAI for Healthcare enables secure, enterprise-grade AI that supports HIPAA compliance—reducing administrative burden and supporting clinical workflows.
OpenAI Blog
Dec 16, 2025
Evaluating AI’s ability to perform scientific research tasks
OpenAI introduces FrontierScience, a benchmark testing AI reasoning in physics, chemistry, and biology to measure progress toward real scientific research.
OpenAI Blog
Jun 17, 2024
Using GPT-4o reasoning to transform cancer care
Color Health is working with OpenAI to pioneer a new way of accelerating cancer patients’ access to treatment. Their new Cancer Copilot application uses GPT-4o to identify missing diagnostics and create tailored workup plans, enabling healthcare providers to make evidence-based decisions about cancer screening and treatment.
OpenAI Blog
Jul 22, 2025
Pioneering an AI clinical copilot with Penda Health
OpenAI and Penda Health debut an AI clinical copilot that cuts diagnostic errors by 16% in real-world use—offering a new path for safe, effective AI in healthcare.
arXiv AI
Jul 2
RareDxR1: Autonomous Medical Reasoning for Rare Disease Diagnosis Beyond Human Annotation
arXiv:2607. 00147v1 Announce Type: new Abstract: Rare disease differential diagnosis is a critical yet arduous clinical task, requiring physicians to identify precise phenotypes from complex, unstructured patient symptoms and execute intricate reasoning within a vast search space.
arXiv AI
1d ago
DiagnosisArena: Benchmarking Diagnostic Reasoning for Large Language Models
arXiv:2505. 14107v5 Announce Type: replace-cross Abstract: The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios.
OpenAI Blog
Aug 6
Working with the American Psychological Association on youth mental health and AI
OpenAI and the American Psychological Association advance evidence-based guidance, resources, and safeguards for responsible AI use and youth mental health.