OpenAI introduces FrontierScience, a benchmark testing AI reasoning in physics, chemistry, and biology to measure progress toward real scientific research.
OpenAI introduces a real-world evaluation framework to measure how AI can accelerate biological research in the wet lab. Using GPT-5 to optimize a molecular cloning protocol, the work explores both the promise and risks of AI-assisted experimentation.
OpenAI’s latest line of reasoning models will be used by nation’s leading scientists to drive scientific breakthroughs.
OpenAI outlines its commitment to advancing American science working with the U. S.
OpenAI introduces the first research cases showing how GPT-5 accelerates scientific progress across math, physics, biology, and computer science. Explore how AI and researchers collaborate to generate proofs, uncover new insights, and reshape the pace of discovery.
OpenAI is giving 100,000 academic researchers free access to ChatGPT's most advanced AI models to accelerate scientific research, collaboration, and discovery.
The article discusses how coding agents are transforming AI research within OpenAI. It presents early data on agent usage, experiment velocity, task complexity, and the resulting acceleration of research. The piece highlights the growing role of these agents in speeding up development and experimentation.
OpenAI and the Lenfest Institute AI Collaborative and Fellowship program
OpenAI reflects on ten years of progress, from early research breakthroughs to widely used AI systems that reshaped what’s possible. We share lessons from the past decade and why we remain optimistic about building AGI that benefits all of humanity.
The paper introduces ScientistTwo, a fully autonomous multi‑agent framework that takes a scientific problem, establishes baselines, generates hypotheses, and coordinates specialized agents to conduct an end‑to‑end discovery cycle without human intervention. It rigorously tests and refines its methods through automated experiments, ablation studies, and a closed‑loop peer‑review engine. Benchmarking against top conferences (ICLR, ICML, NeurIPS) shows that ScientistTwo produces expert‑level, publishable papers and codebases that outperform human state‑of‑the‑art models and receive higher review ratings under automated AI review.
arXiv:2610.00492v1 Announce Type: cross Abstract: When Isaac Newton discovered the law of gravitation, he did so through an iterative process of analyzing observed data such as planetary patterns, fi...
The paper "The AI-Enabled Scientific Frontier" analyzes 2,507 head‑to‑head comparisons of AI versus other scientific methods across 27 disciplines from 2000 to early 2025. It finds that AI often outperforms traditional statistics but at higher computational cost, while in about a quarter of cases AI is both more expensive and less effective. Compared to scientific computing, AI usually underperforms but at lower cost, though since 2020 its performance has improved, now surpassing computing in over half of the comparisons.
OpenAI and the U. S.