arXiv:2608.23936v1 Announce Type: new
Abstract: We present a dynamical-systems based model for resting-state functional magnetic resonance imaging (rs-fMRI), trained on a dataset of roughly 40K rs-fM...
By Sourav Pal, Viet Luong, Hoseok Lee, Tingting Dan, Guorong Wu, Richard Davidson, Won Hwa Kim, Vikas Singh
arXiv:2607.11295v2 Announce Type: replace
Abstract: Biomedical imaging data exhibit substantial acquisition variability, where identical biological structures can appear markedly different due to dif...
By Mehmet Yigit Avci, Pedro Borges, Virginia Fernandez, Natalia Glazman, Paul Wright, Mehmet Yigitsoy, Sebastien Ourselin, Jorge Cardoso
arXiv:2606. 11107v1 Announce Type: cross Abstract: Clinicians diagnose brain tumors by synthesizing patient symptoms, medical history, and quantitative imaging data from modalities such as MRI and CT scans into a unified clinical judgement.
By Wajih ul Islam, Muhammad Yaqoob, Javed Ali Khan, Volker Steuber
The paper introduces Neuro‑JEPA, a sparse multimodal foundation model that learns unified representations of brain MRI across T1w, T2w, and FLAIR sequences using a latent predictive objective and a Mixture‑of‑Experts architecture. It was pretrained on over 1.5 million scans from 428,647 studies and systematically evaluates architectural, masking, objective, and sparsity choices for robust multimodal representation learning. Across 47 tasks from three health systems and 12 public datasets, Neuro‑JEPA consistently outperforms a simple CNN baseline, demonstrating its effectiveness for both clinical and research applications.
By Haoxu Huang, Long Chen, Jingyun Chen, Jinu Hyun, James Ryan Loftus, Kara Melmed, Daniel Orringer, Jennifer Frontera, Seena Dehkharghani, Arjun Masurkar, Narges Razavian
arXiv:2505. 06945v5 Announce Type: replace Abstract: Multimodal data modeling has emerged as a powerful approach in clinical research, enabling the integration of diverse data types such as imaging, genomics, wearable sensors, and electronic health records.
By Maryam Farhadizadeh, Maria Weymann, Michael Bla{\ss}, Johann Kraus, Christopher Gundler, Sebastian Walter, Noah Hempen, Hannah Bast, Harald Binder, Nadine Binder
arXiv:2607. 26746v1 Announce Type: cross Abstract: Accurate identification of Alzheimers disease (AD) using resting-state functional magnetic resonance imaging (rs-fMRI) remains challenging due to the high dimensionality, noise, and complex inter-regional dependencies inherent in functional brain connectivity, which limit the effectiveness of traditional approaches based on handcrafted connectivity features or conventional machine learning models.
By Harshiddhi Pathak, Gowtham Reddy N, Mrinal Acharya, Manjunatha Mahadevappa
arXiv:2604. 27277v3 Announce Type: replace-cross Abstract: Brain MRI underpins a wide range of neuroscientific and clinical applications, yet most learning-based methods remain task-specific and require substantial labeled data.
By Yizhou Wu, Shansong Wang, Yuheng Li, Mojtaba Safari, Mingzhe Hu, Chih-Wei Chang, Harini Veeraraghavan, Xiaofeng Yang
arXiv:2606. 11500v1 Announce Type: cross Abstract: The success of large-scale deep learning models in neuroscience is fundamentally constrained by severe data heterogeneity.
By Mo Wang, Wenhao Ye, Junfeng Xia, Minghao Xu, Hongkai Wen, Quanying Liu
This study introduces a self‑supervised, physics‑guided deep‑learning framework that converts standard clinical T1‑, T2‑, and FLAIR MRIs into quantitative T1, T2, and proton‑density maps. Trained on 4,121 scan sessions from four different 3 T scanners over six years, the method produces maps whose white‑ and gray‑matter values fall within literature ranges and shows minimal variation across scanner hardware and acquisition protocols (coefficients of variation ≤ 1.1 %). Voxel‑wise reproducibility is high, with Pearson and concordance correlation coefficients above 0.82 for T1 and T2 and mean relative differences below 6 % for T2.
By Jelmer van Lune, Stefano Mandija, Oscar van der Heide, Matteo Maspero, Martin B. Schilder, Jan Willem Dankbaar, Cornelis A. T. van den Berg, Alessandro Sbrizzi
arXiv:2506.20354v3 Announce Type: replace-cross
Abstract: Learning from multi-variate time-series with heterogeneous channel configurations remains a fundamental challenge for deep neural networks, p...
By Francesco Carzaniga, Michael Hersche, Abu Sebastian, Kaspar Schindler, Abbas Rahimi
Multimodal fusion learning (MFL) has shown great potential in the medical domain, where we are faced with disparate data modalities such as imaging, clinical records, and omics. However, existing MFL strategies face several major challenges.
The paper introduces CoMA-DiT, a bidirectional cross‑modal Diffusion Transformer that uses paired modalities as mutual generative supervision for latent augmentation rather than just inputs for fusion. By conditioning velocity prediction on the paired modality through cross‑modal attention and injecting variation via a reliability‑gated residual mechanism, CoMA‑DiT improves multimodal brain state decoding. Experiments on auditory attention decoding and emotion recognition show consistent gains over 20 baselines, with absolute accuracy and macro‑F1 improvements of 4.28% and 6.70% respectively, and extensive analyses confirm its robustness and interpretability.
By Ziwei Wang, Xingyi He, Hongbin Wang, Tianwang Jia, Bohan Fang, Dongrui Wu