Three-Dimensional Retinal Microvasculature Restoration in OCT Angiography
arXiv:2606. 05375v1 Announce Type: cross Abstract: Optical coherence tomographic angiography (OCTA) is a powerful technique for imaging retinal microvasculature.
arXiv:2608. 15626v1 Announce Type: new Abstract: Optical coherence tomography angiography (OCTA) images retinal blood flow, giving capillary-perfusion and foveal-avascular-zone biomarkers that grade diabetic-retinopathy ischemia.
arXiv:2606. 05375v1 Announce Type: cross Abstract: Optical coherence tomographic angiography (OCTA) is a powerful technique for imaging retinal microvasculature.
arXiv:2607. 03959v1 Announce Type: cross Abstract: Diabetic retinopathy (DR) is a leading cause of vision impairment worldwide, highlighting the need for accurate and accessible screening tools.
arXiv:2609.12574v1 Announce Type: new Abstract: Ultra-widefield (UWF) swept-source optical coherence tomography angiography (SS-OCTA) enables large-area retinal vascular imaging, yet vessel segmentat...
This study presents four deep‑learning pipelines—two‑dimensional and three‑dimensional—for segmenting age‑related macular degeneration (AMD) and diabetic macular edema (DME) lesions in optical coherence tomography (OCT) images. The models achieve Dice scores between 0.76 and 0.82 and demonstrate strong volumetric and surface calibration (r_vol, r_surf ≥ 0.97) on an in‑domain validation set. Generalization was assessed on the OLIVES clinical cohort using proxy metrics such as biomarker AUROC, central subfield thickness correlation, and longitudinal concordance, showing that the predictions still track clinical biomarkers outside the training distribution, albeit with reduced strength.
The study introduces an explainable OCTA pipeline for Alzheimer’s disease phenotyping that combines vessel segmentation, layer‑specific biomarker extraction, and label‑free phenotyping with large language model (LLM) reporting. Using 117 images from 39 subjects, the segmentation models achieved high ROC‑AUC (0.916–0.970) and Dice scores (0.695–0.781), and six vascular biomarkers were used to create subject‑level profiles for exploratory clustering. LLMs (GPT, Gemini, Llama) produced measurement‑grounded reports evaluated for citation faithfulness and diagnostic caution, offering a transparent, non‑diagnostic link between retinal vascular data and Alzheimer’s research.
arXiv:2606. 16234v1 Announce Type: cross Abstract: Fundus fluorescein angiography (FFA) is critical for assessing retinal vascular abnormalities, but its acquisition is invasive and not always feasible.
arXiv:2602.08580v4 Announce Type: replace-cross Abstract: Automatic extraction of retinal vascular biomarkers from color fundus images (CFI) is crucial for large-scale studies of the retinal vasculat...
arXiv:2606. 18876v1 Announce Type: cross Abstract: Optical coherence tomography (OCT) is essential in ophthalmology, but inconsistent image quality especially in low-cost devices hinders automated analysis.
arXiv:2609.09634v1 Announce Type: new Abstract: Large networks and ensembles often lead medical image segmentation challenges, but their storage and inference demands complicate deployment. We presen...
arXiv:2609.24049v1 Announce Type: new Abstract: Accurate retinal vessel segmentation is important for computer-aided ophthalmic analysis, yet thin vessels, low contrast, and severe foreground-backgro...
arXiv:2607. 29337v1 Announce Type: cross Abstract: Background and Objective: Generating realistic medical images with anatomically accurate segmentation masks helps address the shortage of annotated data in medical imaging, particularly in optical coherence tomography (OCT) of mouse eyes, where manual retinal layer delineation is labour-intensive due to tiny structures and required expertise, resulting in scarce datasets.
VeCAS is a two‑stage framework that generates contrast‑free X‑ray angiograms from non‑contrast images. Stage I localizes vascular structures using a discriminative model and cross‑modality latent distillation, while Stage II synthesizes angiographic appearance within those regions with a vessel‑focused inpainting model. Experiments on a lower‑limb vascular intervention dataset show that VeCAS improves vascular structural fidelity and image quality, and robotic guidewire navigation tests demonstrate significant reductions in time to target and operation steps.