The verbose context problem occurs when structured concepts have token-inefficient textual representations. This bottleneck is acute in population health: cohort-level analysis of longitudinal patient records requires reasoning over thousands of medically-coded events, often exceeding 400K tokens in total.
arXiv:2606. 26105v1 Announce Type: cross Abstract: Large language models (LLMs) exhibit strong capabilities in short-context reasoning but degrade in performance over long conversational horizons due to context window limitations and inefficient token usage.
By Derek Thomas
arXiv:2607. 22566v1 Announce Type: new Abstract: MedLoCoMo is a Medical Long-Context Memory benchmark for patient-specific clinical reasoning over multi-admission medical dialogue.
By Zeyu Zhang, Ziqing Wang, Kaize Ding
arXiv:2608. 05375v1 Announce Type: new Abstract: Clinical machine learning (ML) has the potential to support high-stakes medical decision-making, but reliable deployment is often constrained by scarce, heterogeneous, and temporal complexity.
By Ruilin Wang, Bo-Hong Wang, Elizabeth Kourbatski, Jun Bai, Hegang Chen, Ziyang Song, Gilles Boire, Marie Hudson, Yue Li
arXiv:2603. 03292v3 Announce Type: replace-cross Abstract: Large Language Models (LLMs) exhibit high reasoning capacity in medical question-answering, but their tendency to produce hallucinations and outdated knowledge poses critical risks in healthcare fields.
By Wenhao Wu, Zhentao Tang, Yafu Li, Shixiong Kai, Mingxuan Yuan, Zhenhong Sun, Chunlin Chen, Zhi Wang
HERMES is a graph-based framework that uses only clinical text to predict patient outcomes. It builds personalized Knowledge Graphs from clinical notes via Large‑Language‑Model‑guided extraction and Contrastive Logic Modeling, capturing temporal dynamics and treatment changes. A Graph Attention Network then synthesizes patient representations, and experiments on MIMIC‑III and MIMIC‑IV show HERMES outperforms text‑only baselines for in‑hospital mortality and 30‑day readmission prediction.
By Gia-Bach Nguyen, Hoang-Ha Nguyen, Tuan-Cuong Vuong, Trang Mai Xuan, Duy Quoc Ngo, Tien-Cuong Nguyen, Huan Vu, Thien Van Luong
ClinicalGPT‑R1 is a reasoning‑enhanced generalist large language model designed for disease diagnosis. It was trained on 20,000 real‑world clinical records and uses diverse training strategies to improve diagnostic reasoning. In benchmarks, it outperforms GPT‑4o on Chinese diagnostic tasks and matches GPT‑4 performance in English, demonstrating superior disease‑diagnosis capabilities.
By Wuyang Lan, Wenzheng Wang, Changwei Ji, Guoxing Yang, Yongbo Zhang, Xiaohong Liu, Luonan Chen, Shengge Li, Song Wu, Guangyu Wang
arXiv:2604. 06684v2 Announce Type: replace Abstract: Clinical reasoning over electronic health records (EHRs) is a fundamental yet challenging task in modern healthcare.
By Yue Fang, Weibin Liao, Yuxin Guo, Jiaran Gao, Hongxin Ding, Jinyang Zhang, Xinke Jiang, Zhibang Yang, Junfeng Zhao, Yasha Wang, Liantao Ma
arXiv:2505. 14107v5 Announce Type: replace-cross Abstract: The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios.
By Yakun Zhu, Zhongzhen Huang, Linjie Mu, Yutong Huang, Wei Nie, Jiaji Liu, Shaoting Zhang, Pengfei Liu, Xiaofan Zhang
Understanding the temporal progression of symptoms in clinical narratives is critical for disease monitoring, safety surveillance, and causality assessment. Clinical narratives, however, rarely provide explicit temporal anchors.
arXiv:2608.20887v1 Announce Type: cross
Abstract: Automatic Medical Coding (AMC), which assigns standardized International Classification of Diseases (ICD) codes to clinical notes, is essential for m...
By Xubin Chen, Yipeng Zhou, Wen Sun, Chengkai Huang, Xiaoming Fu, Quan Z. Sheng
arXiv:2609.24480v1 Announce Type: cross
Abstract: Deploying Large Language Models (LLMs) in healthcare requires robust performance across two complementary dimensions - diagnostic reasoning: the conv...
By Kalash Shah, Kunal Singh, Snehan J, Shreyas Singh