arXiv AI

Toward System One Clinical Intelligence: Parameter-Efficient Fine-Tuning and Counterfactual Explainability of Decision Foundation Models

arXiv Computation and Language
Oct 22

Is a 9B Decision Foundation Model Needed for Symptom-to-Disease Classification? Fine-Tuning Clef-Flash Against TF-IDF Baselines

The paper evaluates whether a 9‑billion parameter decision foundation model, Clef‑Flash, is necessary for symptom‑to‑disease classification. Fine‑tuning the model on the 24‑class Symptom2Disease benchmark yields 95.42% accuracy, but simple TF‑IDF linear classifiers achieve higher accuracy (98.75%) with far faster inference. Ablation studies show that predictions can hinge on single descriptive clauses, indicating that the benchmark may not fully capture the model’s capabilities.

By S. M. Mahbub Uddin Ahmed
arXiv Machine Learning
Jul 9

Counterfactual Modeling with Fine-Tuned LLMs for Health Intervention Design and Sensor Data Augmentation

arXiv:2601. 14590v3 Announce Type: replace Abstract: Counterfactual explanations (CFEs) provide human-centric interpretability by identifying the minimal, actionable changes required to alter a machine learning model's prediction.

By Shovito Barua Soumma, Asiful Arefeen, Stephanie M. Carpenter, Melanie Hingle, Hassan Ghasemzadeh
arXiv AI
Jun 30

Primary ICD Category Prediction using LLM-based Probing

arXiv:2606. 28798v1 Announce Type: new Abstract: Objective: ICD codes are central to reimbursement, research, and population health surveillance, yet automated coding systems often struggle to integrate diagnostic signals from both clinical narratives and structured electronic health record (EHR) variables.

By Chengyuan Liu, Xinyue Zhang, Yao Li, Guanting Chen
arXiv AI
Jul 21

Retrieval-Augmented Interpretable Learning: Towards Task-Specific Zero-Shot Models in Healthcare

arXiv:2607. 17508v1 Announce Type: cross Abstract: We introduce Retrieval-Augmented Interpretable Learning (RAIL), a probabilistic meta-learning framework for zero-shot generation of task-specific interpretable models that synthesizes coefficient-space structure from natural-language task descriptions and a memory of previously learned task-specific predictors.

By Sazan Mahbub, Caleb Ellington, Zhiyuan Li, Yixin Yang, Souvik Kundu, Ben Lengerich, Eric P. Xing
arXiv AI
Jul 29

Aletheia: An Offline-First Clinical Decision Support System for Differential Diagnosis in Low-Resource Healthcare Settings

arXiv:2607. 24814v1 Announce Type: new Abstract: Access to specialist clinical expertise remains severely limited across sub-Saharan Africa, where physician-to-patient ratios can fall below 1:25,000 in rural settings.

By Joseph Walusimbi, Ann Move Oguti, Abubakhari Sserwadda, Precious Boss Kasasira, Charles Brian Okoboi
arXiv AI
Jun 8

REMEDI: A Benchmark for Retention and Unlearning Evaluation in Multi-label Clinical Disease Inference

arXiv:2606. 07141v1 Announce Type: cross Abstract: Language models trained for clinical disease inference are trained on patient data, which may include sensitive and private information, and data owners may request the removal of their data from a trained model due to privacy or copyright concerns.

By Anurag Sharma, Sai Teja Chunchu, Prasenjit Mitra, Sandipan Sikdar, Koustav Rudra