Multimodal Large Language Models (MLLMs) have shown promising reasoning capabilities in general domains, yet their performance remains limited in specialized settings such as healthcare, especially in multilingual and low-resource scenarios. This gap is critical in regions like rural India, where patients often express complex medical queries in native Indic languages and rely on multimodal inputs such as medical images.
Lingshu is a medical‑specialized multimodal large language model that addresses key limitations of existing medical MLLMs, such as narrow knowledge coverage, hallucinations, and weak reasoning. The authors curate a comprehensive dataset combining medical imaging, texts, and general‑domain data, then train Lingshu in multiple stages to embed medical expertise and improve task performance. They also introduce MedEvalKit, a unified evaluation framework, and demonstrate that Lingshu outperforms current open‑source multimodal models on multimodal QA, text‑based QA, and medical report generation.
By Weiwen Xu, Hou Pong Chan, Long Li, Mahani Aljunied, Ruifeng Yuan, Jianyu Wang, Chenghao Xiao, Guizhen Chen, Chaoqun Liu, Zhaodonghui Li, Yu Sun, Junao Shen, Chaojun Wang, Jie Tan, Deli Zhao, Tingyang Xu, Hao Zhang, Yu Rong
MMTClinic is a new benchmark that tests large language models on complex reasoning and question‑answering tasks involving clinical time‑series data. It combines text, medical images, and multivariate physiological signals to create 30,000 QA pairs—including 15,000 multiple‑choice and 15,000 open‑ended questions—in five languages (English, Hindi, Bengali, Marathi, and Tamil). The benchmark covers mortality prediction, heart‑rate forecasting, and SOFA score estimation, and evaluates 13 state‑of‑the‑art LLMs across zero‑shot, few‑shot, and chain‑of‑thought settings, revealing significant performance gaps across tasks, languages, and modalities.
By Sourav Malakar, Harshit Nigam, Akash Ghosh, Sriparna Saha, Amlan Chakrabarti, Saptarsi Goswami, Priti Singh
The paper introduces a method for generating multilingual reasoning traces for medical question answering using large language models. It creates 500,000 reasoning traces in English, Italian, and Spanish by retrieving medical information from Wikipedia and applies them to MedQA and MedMCQA datasets extended into Italian and Spanish. The approach improves performance in both few‑shot in‑context learning and supervised fine‑tuning, achieving state‑of‑the‑art results for 8B‑parameter LLMs and releasing all resources for further research.
By Pietro Ferrazzi, Aitor Soroa, Rodrigo Agerri
arXiv:2601. 02854v2 Announce Type: replace Abstract: As an agent-level reasoning and coordination paradigm, Multi-Agent Debate (MAD) orchestrates multiple agents through structured debate to improve answer quality and support complex reasoning.
By Ao Li, Jinghui Zhang, Luyu Li, Yuxiang Duan, Lang Gao, Mingcai Chen, Weijun Qin, Shaopeng Li, Fengxian Ji, Ning Liu, Lizhen Cui, Xiuying Chen, Yuntao Du
arXiv:2606. 28556v1 Announce Type: new Abstract: Recent advances in large language models and vision-language models have enabled reasoning over multimodal data, offering opportunities for clinical applications such as decision support and triaging.
By Maria Xenochristou, Ashutosh Joshi, Korosh Vatanparvar, Mohammad Abuzar Hashemi, Prasad Kasu, Deepak Bansal, Anchal Nema, Nivedita Wadhwa, Prashams S Jain, Rebecca Abraham, Will Kimbrough, Dilek Hakkani-Tur, Wilko Schulz-Mahlendorf
The paper introduces MedREAL, a unified framework that aligns linguistic reasoning with spatial grounding for medical visual question answering and segmentation. MedREAL employs Seg Anchored Reasoning Pooling (SARP) to extract semantic evidence from segmentation tokens and a Reasoning-to-Visual (R2V) fusion mechanism to integrate these features into a segmentation pipeline. Using the newly created MedRAVS-13K dataset, MedREAL achieves superior performance, reporting 68.49% gIoU and 70.47% cIoU, and generates evidence masks that consistently match textual diagnoses.
By Haowen Gu, Gensheng Pei, Junzhu Mao, Qiong Wang, Mingwu Ren, Yazhou Yao
The paper introduces MedUAG, a unified medical multimodal model that supports both understanding and generation tasks. It presents MedUAGCorpus, the largest dataset of over 6 million instances across 14 imaging modalities, and MedUAGBench, a benchmark covering 12 diverse generation tasks with standardized protocols. Experiments show that MedUAG performs strongly across many medical understanding and generation tasks, setting a competitive baseline for future medical multimodal systems.
By Zijie Meng, Yuncheng Zhang, Hualiang Wang, Yitian Tang, Xiaotang Gai, Chen Shen, Songtao Jiang, Shaosheng Cao, Jian Wu, Xian Wu, Zuozhu Liu
arXiv:2608.21810v1 Announce Type: cross
Abstract: Clinical decision-making is inherently experience-driven: physicians progressively refine their reasoning by synthesizing patient history, multimodal...
By Md Asaduzzaman Jabin, Khoa Le, Lin Zhao, Tianming Liu
arXiv:2512. 01045v2 Announce Type: replace Abstract: Data-intensive artificial intelligence applications increasingly rely on large-scale, high-quality, explainable, and reproducible datasets, yet the construction of such datasets often remains labor-intensive, weakly traceable, and difficult to configure.
By Shenxi Liu, Kan Li, Mingyang Zhao, Yuhang Tian, Bin Li
DocTalkBN is a large-scale multimodal dataset of authentic expert telemedicine conversations in Bengali, comprising 557.63 hours of paired audio and text, 1,515 multi-turn patient calls, and 10,274 host–doctor question–answer exchanges across 26 medical specialties. The dataset contains 1.7 million tokens and preserves the spontaneity and contextual richness of real medical interactions in a low-resource language. Three downstream tasks—medical triage classification, advice safety evaluation, and medical named entity recognition—are constructed to benchmark large language models and encoder-based baselines, demonstrating DocTalkBN’s practical usefulness for clinically grounded reasoning.
By Anik Saha, Fahmida Sultana Naznin, Sadatul Islam Sadi, Ananya Shahrin Promi, Wahid Al Azad Navid, Rifat Shahriyar
arXiv:2607. 25947v1 Announce Type: new Abstract: Question answering (QA) over irregular clinical time series (ICTS) plays a pivotal role in a wide range of healthcare applications.
By Frank Nie, Ethan B Liu, Yuan Zhu, Wei Fan, Jindong Han