arXiv AI

Beyond Continuity: Simulation-free Reconstruction of Discrete Branching Dynamics from Single-cell Snapshots

arXiv:2605. 00545v2 Announce Type: replace-cross Abstract: Inferring cellular trajectories from destructive snapshots is complicated by the challenges of stochasticity and non-conservative mass dynamics such as cell proliferation and apoptosis.

arXiv Machine Learning
Jun 2

Flow-Based Density Ratio Estimation for Intractable Distributions with Applications in Genomics

arXiv:2602. 24201v2 Announce Type: replace Abstract: Estimating density ratios between pairs of intractable data distributions is a core problem in probabilistic modeling, enabling principled comparisons of sample likelihoods under different data-generating processes across conditions.

By Egor Antipov, Alessandro Palma, Lorenzo Consoli, Stephan G\"unnemann, Andrea Dittadi, Fabian J. Theis
arXiv Machine Learning
Jul 21

Twisted Schr\"odinger Bridge Matching

arXiv:2607. 16987v1 Announce Type: cross Abstract: Over the past few years, diffusion-based Schr\"odinger bridge models have been proposed to approximate optimal transport dynamics between two prescribed boundary distributions, with successful applications to generative modeling.

By Maxence Noble, Marie Scheid, Yazid Janati, Eric Moulines, Alain Durmus
arXiv AI
Jun 8

CountsDiff: A Diffusion Model on the Natural Numbers for Generation and Imputation of Count-Based Data

arXiv:2604. 03779v2 Announce Type: replace-cross Abstract: Diffusion models have excelled at generative tasks for both continuous and token-based domains, but their application to discrete ordinal data remains underdeveloped.

By Renzo G. Soatto, Anders Hoel, Greycen Ren, Shorna Alam, Stephen Bates, Nikolaos P. Daskalakis, Caroline Uhler, Maria Skoularidou
arXiv AI
Jun 30

Enhanced Diffusion Sampling: Efficient Rare Event Sampling and Free Energy Calculation with Diffusion Models

arXiv:2602. 16634v2 Announce Type: replace-cross Abstract: The rare-event sampling problem has long been the central limiting factor in molecular dynamics (MD), especially in biomolecular simulation.

By Yu Xie, Ludwig Winkler, Lixin Sun, Sarah Lewis, Adam E. Foster, Jos\'e Jim\'enez Luna, Tim Hempel, Michael Gastegger, Yaoyi Chen, Iryna Zaporozhets, Cecilia Clementi, Christopher M. Bishop, Frank No\'e
arXiv Machine Learning
Jun 30

Neural Galerkin Normalizing Flow for Transition Probability Density Functions of Diffusion Models

arXiv:2603. 18907v2 Announce Type: replace Abstract: We propose a new Neural Galerkin Normalizing Flow framework to approximate the transition probability density function of a diffusion process by solving the corresponding Fokker-Planck equation with an atomic initial distribution, parametrically with respect to the location of the initial mass.

By Riccardo Saporiti, Fabio Nobile