arXiv AI

LAP: An Agent-to-Instrument Protocol for Autonomous Science

arXiv:2606. 03755v1 Announce Type: new Abstract: Autonomous science is moving from demonstration to infrastructure.

arXiv AI
Jul 1

A Self-Evolving Agentic System for Automated Generation and Execution of Biological Protocols

arXiv:2606. 31763v1 Announce Type: new Abstract: Autonomous wet-lab experimentation requires more than plausible protocol text: biological intent, quantitative procedures, device constraints and experimental feedback must remain aligned from protocol and SOP design to code and physical execution.

By Yankai Jiang, Weiting Tang, Haoran Sun, Zhenyu Tang, Yuejie Hou, Yingnan Han, Rubo Wang, Yueyuxiao Yang, Cheng Liang, Lilong Wang, Wenjie Lou, Xiaosong Wang, Lei Bai, Meng Yang
arXiv AI
Sep 2

Towards Agentic Cloud Engineering: Graph and Loop Engineering with a Zero-Trust Agent Harness

The paper introduces Agentic Cloud Workflow Engineering, a framework that converts natural‑language agentic cloud‑engineering tasks into validated code repositories and verified cloud deployments. It separates graph engineering for long‑horizon workflow progression, loop engineering for bounded diagnosis and recovery, and agent harness engineering for zero‑trust execution. Experiments on Google Cloud show that executions either produce a verified deployment or an auditable terminal failure within bounded recovery limits.

By Sagar Srinivas Sakhinana, Venkataramana Runkana
arXiv AI
Sep 7

La Agente \'Optima: Towards Agentic Self-Driving Laboratories

La Agente ’Optima is an agentic framework that builds and manages Bayesian optimization campaigns for self‑driving laboratories, separating large language model reasoning from campaign execution. It maintains a persistent optimization state, allowing consistent repetitive loops and auditable decisions, and only returns control to the agent when interpretation or revision is needed. In tests on digital discovery tasks and physical platforms, it corrected measurement failures, improved yields, and recommended formulation changes, outperforming human‑directed campaigns in cost and material usage.

By Marcel M\"uller, Jiaru Bai, Willi Gottstein, Abhijoy Mandal, Mohammad Nazeri, Elia Savino, Yanlin Fang, Sujoy Das, Sergio Pablo Garc\'ia Carrillo, Yeonghun Kang, Juan B. P\'erez-S\'anchez, Simone Pilon, Martin Fitzner, Timothy No\"el, Frank Gu, Varinia Bernales, Al\'an Aspuru-Guzik
arXiv AI
Sep 4

A computable representation of the physical laboratory enables verifiable workflows

The paper introduces a computable representation of the physical laboratory that combines typed research objects, capability‑bound operations, and a compositional workflow algebra. This framework allows scientific workflows to be expressed as programs that track evolving laboratory states, including explicit dependencies, decisions, iteration, and concurrency. Implemented in a modular agentic robotic laboratory, the system binds formal operations to executable Function Skills, generates capability‑relative workflows for diverse scientific goals, and uses stateful simulation to verify operation preconditions and laboratory constraints before execution.

By Xiaobo Li, Luyao Ge, Xiaohui Li, Lulu Guo, Ming Mao, Jiwang Zheng, Wenting Guan, Xin Yang, Yi Luo, Jun Jiang, Linjiang Chen
arXiv AI
6d ago

A Safety-Bounded SDC-to-MCP Gateway for Medical AI Agents

The paper introduces a safety‑bounded gateway that translates IEEE 11073 Service‑Oriented Device Connectivity (SDC) into the Model Context Protocol (MCP) for medical AI agents. It exposes device metrics, alarms, context references, and semantic metadata as read‑only resources, while representing selected action affordances as policy‑validated dry‑run tools, ensuring that agent requests never trigger actual device operations. A Python prototype demonstrates fault and lifecycle experiments, deterministic baselines, and multi‑model agent evaluation, showing improved semantic conformity and preservation of the no‑execution boundary.

By Bennet Gerlach, Stefan Fischer
arXiv AI
Jul 14

AgentAbstain: Do LLM Agents Know When Not to Act?

arXiv:2607. 10059v1 Announce Type: new Abstract: Agent systems based on large language models (LLMs) are increasingly deployed for autonomous tasks, yet existing evaluations mostly focus on task success rather than whether agents know when to abstain.

By Xun Liu, Yi Evie Zhang, Vira Kasprova, Parisa Rabbani, Pardis Sadat Zahraei, Tianyu Zhang, Ali Ebrahimpour-Boroojeny, Varun Chandrasekaran
arXiv AI
Sep 7

From Language Models to World-Acting Systems: Progress and Limits of Agentic AI across Digital, Social, Virtual, and Physical Environments

The paper reviews how large language models have evolved into agents that can influence external environments through tool use, interface operation, delegation, state retention, virtual world inhabitation, and robotic control. It critiques the narrative of a single march toward autonomy, distinguishing model competence from system integration, persistence, and safe authority. The authors find that action-interface expansion is well documented, while robust completion, recovery, authorization, and independent verification remain less proven, and they propose a framework of justified delegation to guide future research.

By Linsen Zhu, Mengqing Cai