The paper presents the first systematic evaluation of out‑of‑distribution generalization for congenital heart disease (CHD) segmentation, using the ImageCHD cohort as a held‑out target. It compares several segmentation architectures under different training regimes, showing that in‑distribution performance is a poor predictor of cross‑cohort robustness: nnU‑Net drops from 0.77 to 0.51 Dice, while SwinUNETR maintains higher performance at 0.67 Dice. Limited target‑domain adaptation with only 11 labeled ImageCHD cases boosts all SwinUNETR variants above 0.76 Dice, highlighting the importance of explicit cross‑dataset testing.
By Aniketh Vijesh, Shrisharanyan Vasu, Abhijit Ramesh, Clare Pomeroy-Ward, Harikrishnan Anil Maya, Sarin Xavier, Mahesh Kappanayil, Gilad Gressel
Congenital heart disease (CHD) diagnosis and surgical planning often require patient-specific 3D anatomical models, but manual segmentation is labor-intensive, particularly in complex anatomies. Altho...
arXiv:2608.31073v1 Announce Type: new
Abstract: Whole-heart segmentation (WHS) in computed tomography (CT) and magnetic resonance imaging (MRI) is affected by acquisition shifts and heterogeneous car...
By Jiacheng Wang, Ivana Isgum, Ipek Oguz
arXiv:2602.20773v2 Announce Type: replace
Abstract: Purpose: Developing generalizable medical image segmentation models is challenging because imaging data are distributed across institutions and dif...
By Sachin Dudda Nagaraju, Ashkan Moradi, Bendik Skarre Abrahamsen, Mattijs Elschot
arXiv:2608.28923v1 Announce Type: cross
Abstract: Data augmentation is a cornerstone of deep learning pipelines, yet existing strategies treat it as a static, model-agnostic preprocessing step, eithe...
By Noah Videcrantz, Mostafa Mehdipour Ghazi
arXiv:2607. 11287v1 Announce Type: cross Abstract: Comprehensive quantification of cardiac structures from computed tomography (CT) remains limited not by data availability but by the scalability of measurements, which makes routine use impractical.
By Pooya Mohammadi Kazaj, Leo Fridolin Weber, Wen Xie, Seyed Amir Ahmad Safavi-Naini, Anselm Stark, Giovanni Baj, Ali Mokhtari, Toshiya Yoshida, Christoph Ryffel, Taishi Okuno, Yoshihiro Akashi, Ronny R. Buechel, Thomas Pilgrim, Waldo Valenzuela, George C. M. Siontis, Xiaowei Xu, Moritz Hundertmark, Stephan Windecker, Christoph Grani, Isaac Shiri
arXiv:2609.08043v1 Announce Type: cross
Abstract: Deep learning has achieved state-of-the-art performance in echocardiographic video segmentation, with an increasing number of models incorporating te...
By Jiyoo Noh, Jonathan H. Chan
arXiv:2608. 10903v1 Announce Type: cross Abstract: Reliable clinical deployment of machine learning requires models that know when they are likely to fail, particularly for subgroups underrepresented in training data.
By Paul Fischer, Ece Ozkan
arXiv:2607. 05008v1 Announce Type: cross Abstract: Echocardiography is the first imaging modality used for assessing cardiac function, and accurate segmentation of cardiac structures is essential for deriving biomarkers.
By Iman Islam, Esther Puyol-Ant\'on, Bram Ruijsink, Andrew J. Reader, Andrew P. King
arXiv:2507. 12645v1 Announce Type: cross Abstract: The increasing need for accurate and unified analysis of diverse biological signals, such as ECG and EEG, is paramount for comprehensive patient assessment, especially in synchronous monitoring.
By Mohammed Guhdar, Ramadhan J. Mstafa, Abdulhakeem O. Mohammed
Echo-E$^3$Net is an anatomy‑guided spatio‑temporal neural network designed to estimate left ventricular ejection fraction (LVEF) from ultrasound images. It uses a dual‑phase Endocardial Border Detector to locate end‑diastole and end‑systole landmarks and an Endocardial Feature Aggregator to fuse these landmarks with global deep‑feature descriptors for EF regression. The model achieves competitive accuracy on EchoNet‑Dynamic and EchoNet‑Pediatric datasets while using only 1.55 M parameters and 8.05 GFLOPs, enabling real‑time deployment on limited‑resource devices.
By Moein Heidari, Afshin Bozorgpour, AmirHossein Zarif-Fakharnia, Wenjin Chen, Dorit Merhof, David J. Foran, Jasmine Grewal, Ilker Hacihaliloglu
The paper presents a modality‑routed 3D cardiac segmentation pipeline that combines TotalSegmentator‑initialized nnU‑Netv2 models with site‑characterized, label‑preserving appearance augmentation. By analyzing measurable image properties across sites, the authors design a bias‑field plus Bezier augmentation strategy that smooths spatial intensity perturbations and remaps intensities nonlinearly, followed by class‑wise largest‑connected‑component cleanup. On held‑out validation splits, this approach raises CT mean Dice from 0.8350 to 0.9135 and MRI mean Dice from 0.7695 to 0.7830 while reducing HD95, demonstrating improved cross‑site robustness in limited‑data whole‑heart segmentation.
By Tanish Mudaliar, Justin Li, Daniel Lin, Julianna Vo, Kaitao Liao, Xin Wang, Shu Hu