arXiv AI

Leveraging Natural Language Processing to Unravel the Mystery of Life: A Review of NLP Approaches in Genomics, Transcriptomics, and Proteomics

arXiv:2506. 02212v2 Announce Type: replace-cross Abstract: Natural Language Processing (NLP) has transformed various fields beyond linguistics by applying techniques originally developed for human language to the analysis of biological sequences.

arXiv AI

Jul 13

TheBioCollection: Unified Pre-Training Scale LLM Corpus for Biology

arXiv:2607. 08803v1 Announce Type: cross Abstract: The push toward large language models for biology (BioLM) has created a need for training corpora that can endow models with a genuine understanding of biology.

By Hyunjin Seo, Hyeon Hwang, Gyubok Lee, Jay Shin, Jimin Park, Taesoo Kim, Sanghoon Lee, Hongjoon Ahn, Sungjun Han, Sangwon Jung

llms

arXiv AI

Jun 30

A Large-Scale Dataset for Molecular Structure-Language Description via a Rule-Regularized Method

arXiv:2602. 02320v4 Announce Type: replace-cross Abstract: Molecular function is largely determined by structure.

By Feiyang Cai, Guijuan He, Yi Hu, Jingjing Wang, Joshua Luo, Tianyu Zhu, Srikanth Pilla, Gang Li, Ling Liu, Feng Luo

llms safety

arXiv AI

Jul 22

Saving the legacy of Hero Ibash: Evaluating Four Language Models for Aminoacian

arXiv:2402. 18121v2 Announce Type: replace-cross Abstract: This study assesses four cutting-edge language models in the underexplored Aminoacian language.

By Yunze Xiao, Yiyang Pan

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arXiv AI

Aug 12

JEPA-DNA: Grounding Genomic Foundation Models through Joint-Embedding Predictive Architectures

arXiv:2602. 17162v3 Announce Type: replace Abstract: Genomic Foundation Models (GFMs) typically rely on Masked Language Modeling (MLM) or Next-Token Prediction (NTP) to learn the "Laws of Nature".

By Ariel Larey, Elay Dahan, Amit Bleiweiss, Raizy Kellerman, Guy Leib, Omri Nayshool, Dan Ofer, Tal Zinger, Dan Dominissini, Gideon Rechavi, Nicole Bussola, Simon Lee, Shane O'Connell, Dung Hoang, Marissa Wirth, Alexander W. Charney, Nati Daniel, Yoli Shavit

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arXiv Machine Learning

Jun 10

Entropy, Disagreement, and the Limits of Foundation Models in Genomics

arXiv:2604. 04287v2 Announce Type: replace Abstract: Foundation models in genomics have shown mixed success compared to their counterparts in natural language processing.

By Maxime Rochkoulets, Lovro Vr\v{c}ek, Mile \v{S}iki\'c

rag nlp

arXiv AI

Jun 18

SciHorizon-GENE: Benchmarking LLM for Life Sciences Inference from Gene Knowledge to Functional Understanding

arXiv:2601. 12805v4 Announce Type: replace-cross Abstract: Large language models (LLMs) have shown growing promise in biomedical research, particularly for knowledge-driven interpretation tasks.

By Xiaohan Huang, Meng Xiao, Chuan Qin, Qingqing Long, Jinmiao Chen, Yuanchun Zhou, Hengshu Zhu

llms benchmarks safety

arXiv AI

Jun 4

BRAINCELL-AID: An Agentic AI Created Brain Cell Type Resource for Community Annotation

arXiv:2510. 17064v4 Announce Type: replace Abstract: Single-cell RNA sequencing has transformed our ability to identify diverse cell types and their transcriptomic signatures.

By Rongbin Li, Wenbo Chen, Zhao Li, Rodrigo Munoz-Castaneda, Jinbo Li, Neha S. Maurya, Arnav Solanki, Huan He, Hanwen Xing, Meaghan Ramlakhan, Zachary Wise, Nelson Johansen, Zhuhao Wu, Hua Xu, Michael Hawrylycz, W. Jim Zheng

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arXiv AI

Jul 16

Improving Molecular Property Prediction in Small Language Models Using Graph-based Tools

arXiv:2607. 13115v1 Announce Type: new Abstract: Small language models (SLMs) have shown promise for zero-shot molecular property prediction from SMILES strings, yet they often suffer from structural blindness because sequence representations under-specify key graph-topological cues.

By Konstantinos Bougiatiotis, Dimitrios Kelesis, Georgios Paliouras

llms agents

arXiv Machine Learning

Aug 4

SIGMA: Semantic Identifier Grouping for Molecular Autoregression

arXiv:2603. 25062v2 Announce Type: replace Abstract: Autoregressive molecular models assign probability to molecular serializations even though chemical identity is invariant to serialization.

By Xinyu Wang, Fei Dou, Jinbo Bi, Minghu Song

benchmarks safety

arXiv AI

Jul 24

Generative Artificial Intelligence in Bioinformatics: A Systematic Review of Models, Applications, and Methodological Advances

arXiv:2511. 03354v2 Announce Type: replace-cross Abstract: Generative artificial intelligence (GenAI) is transforming bioinformatics by advancing genomics, proteomics, transcriptomics, structural biology, and drug discovery.

By Wasimul Karim, Riasad Alvi, Sayeem Been Zaman, Arefin Ittesafun Abian, Mohaimenul Azam Khan Raiaan, Saddam Mukta, Md Rafi Ur Rashid, Md Rafiqul Islam, Yakub Sebastian, Sami Azam

benchmarks safety

arXiv AI

Jun 12

AAbAAC: An Annotated Corpus for Autoimmunity Information Extraction

arXiv:2606. 13051v1 Announce Type: new Abstract: Despite advances in information extraction driven by deep learning and large language models, performance gaps remain in highly specialized biomedical fields, where domainspecific complexity poses challenges for generalist models.

By Fabien Maury (Imagine - U1163, HeKA | U1346), Sol\`ene Grosdidier (Imagine - U1163), Maud de Dieuleveult (Imagine - U1163), Adrien Coulet (HeKA | U1346)

llms nlp fine-tuning

arXiv Machine Learning

Aug 5

Bi-semantic Chemical Embedder for Joint Representation Learning of SMILES and Natural Language

arXiv:2608. 03855v1 Announce Type: new Abstract: Transformer models have revolutionized natural language processing (NLP), and text-based molecular representations like SMILES have successfully extended these architectures to chemistry.

By David Ming Segura, Jeremy Goumaz, Joshua W. Sin, Bojana Rankovi\'c, Philippe Schwaller

llms rag nlp

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