arXiv:2601. 12805v4 Announce Type: replace-cross Abstract: Large language models (LLMs) have shown growing promise in biomedical research, particularly for knowledge-driven interpretation tasks.
By Xiaohan Huang, Meng Xiao, Chuan Qin, Qingqing Long, Jinmiao Chen, Yuanchun Zhou, Hengshu Zhu
arXiv:2603. 11872v3 Announce Type: replace-cross Abstract: Translating single-cell RNA sequencing (scRNA-seq) data into mechanistic biological hypotheses remains a critical bottleneck, as agentic AI systems lack direct access to transcriptomic representations while expression foundation models remain opaque to natural language.
By Omar Coser
arXiv:2605. 07022v3 Announce Type: replace Abstract: Manually curated biomedical repositories -- spanning bioactivity, genomics, and chemistry -- are expensive to maintain, lag behind primary literature, and discard experimental context, obscuring nuances needed to assess data correctness and coverage.
By Haydn Jones, Yimeng Zeng, Alden Rose, Li S. Yifei, Yining Huang, Kaiwen Wu, Jiaming Liang, Maggie Ziyu Huan, Yoseph Barash, Cesar de la Fuente-Nunez, Osbert Bastani, Zachary Ives, Mark Yatskar, Jacob R. Gardner
arXiv:2607. 08803v1 Announce Type: cross Abstract: The push toward large language models for biology (BioLM) has created a need for training corpora that can endow models with a genuine understanding of biology.
By Hyunjin Seo, Hyeon Hwang, Gyubok Lee, Jay Shin, Jimin Park, Taesoo Kim, Sanghoon Lee, Hongjoon Ahn, Sungjun Han, Sangwon Jung
arXiv:2606. 13007v1 Announce Type: cross Abstract: Clustering is fundamental to scRNA-seq analysis, serving as a cornerstone for identifying cell populations and resolving tissue heterogeneity.
By Ping Xu, Pengjiang Li, Tian Du, Zaitian Wang, Jiawei Gu, Ziyue Qiao, Pengfei Wang, Yuanchun Zhou
arXiv:2607. 22770v1 Announce Type: new Abstract: Although artificial intelligence (AI) has shown promising performance in several medical tasks, accurate dementia etiology diagnosis with AI remains challenging due to complex overlapping symptoms among diseases.
By Siyuan Du, Mengxi Chen, Xinyang Jiang, Zilong Wang, Jiangchao Yao, Dongsheng Li, Ya Zhang, Lili Qiu, Yanfeng Wang
arXiv:2606. 01042v1 Announce Type: cross Abstract: Perturbation experiments are central to understanding cellular mechanisms, but remain costly and sparse, motivating prediction of gene expression responses for unobserved conditions.
By Xinyu Yuan, Xixian Liu, Jianan Zhao, Yashi Zhang, Hongyu Guo, Jian Tang
arXiv:2607. 29347v1 Announce Type: cross Abstract: Modern neuroscience relies on integrating multi-scale, multimodal datasets to uncover the neural principles underlying intelligence.
By Jiamin Wu, Peishan Xiang, Jingyang Chen, Yuqing Zhu, Yuxi Li, Ling Luo, Qihao Zheng, Jialiang Zu, Yongchao Wu, Mindong Liu, Haitao Wu, Chaofan Hu, Yijie Sun, Yuqi Hang, Yu Zhu, Shuo Li, Yue Fan, Shiyang Feng, Wanghan Xu, Tianlei Zhang, Jie Zhang, Wenlong Zhang, Bo Zhang, Kai Wang, Lei Bai, Mianxin Liu, Wanli Ouyang, Jiulin Du, Chunfeng Song
arXiv:2603. 03322v2 Announce Type: replace-cross Abstract: Recent advancements in Large Language Model (LLM) agents have demonstrated remarkable potential in automatic knowledge discovery.
By Chaoqun Yang, Xinyu Lin, Shulin Li, Wenjie Wang, Ruihan Guo, Fuli Feng, Tat-Seng Chua
Brain-Computer Interfaces (BCIs) and brain signal understanding are pivotal for clinical health and next-generation interactions. Despite this significance, its widespread adoption in real-world scenarios remains restricted, primarily because current analytical paradigms lack sufficient agentic intelligence.
arXiv:2606. 09558v1 Announce Type: cross Abstract: Motivation: Transformer-based models are increasingly applied to large-scale single-cell transcriptomics, showing strong performance through self-supervised learning on millions of cells.
By Mikele Milia, Louis Fabrice Tshimanga, Henning Mueller, Manfredo Atzori, Barbara Di Camillo
arXiv:2606. 00370v1 Announce Type: cross Abstract: Diverse genomics data, scientific questions, and analysis tasks typically demand highly specialized visualizations.
By Astrid van den Brandt, Kiroong Choe, Sehi L'Yi, Devin Lange, Nils Gehlenborg