Microsoft Research

Introducing CARE-X: Towards Clinically Useful Radiology VLMs with Auxiliary Supervision, Reward-Aligned Learning, and Tool-Augmented Measurement

Radiology AI is evolving beyond report generation. CARE-X explores a unified approach that combines flexible reasoning, calibrated predictions, and measurement-based tools for chest X-ray interpretation.

arXiv AI
Jun 2

RadAgent: A tool-using AI agent for stepwise interpretation of chest computed tomography

arXiv:2604. 15231v2 Announce Type: replace Abstract: Vision-language models (VLM) have markedly advanced AI-driven interpretation and reporting of complex medical imaging, such as computed tomography (CT).

By M\'elanie Roschewitz, Kenneth Styppa, Yitian Tao, Jiwoong Sohn, Jean-Benoit Delbrouck, Benjamin Gundersen, Nicolas Deperrois, Christian Bluethgen, Julia E. Vogt, Bjoern Menze, Farhad Nooralahzadeh, Michael Krauthammer, Michael Moor
arXiv AI
Aug 5

CARE-X: Towards Clinically Useful Radiology VLMs with Auxiliary Supervision, Reward-Aligned Learning, and Tool-Augmented Measurement

arXiv:2608. 03890v1 Announce Type: cross Abstract: A clinically useful chest X-ray system must go beyond fluent report generation: it should classify findings with tunable decision thresholds, localize them spatially, and derive the anatomical measurements upon which many diagnoses depend.

By Mercy Prasanna Ranjit, Anirban Porya, Sathvik Joel, Niharika Vadlamudi, Nikhilesh Chowdary Eathamukkala, Prasanth V V, Abhyuday Kumara Swamy, Pranay Narhari Umredkar, Pradeep Narayan, Vivek Rajagopal, Tanuja Ganu
arXiv AI
Sep 10

A radiographic world model for clinical reasoning and evidence generation

The paper introduces MedDream, a radiographic world model that learns a shared continuous latent state from paired chest radiograph-text observations. MedDream outperforms existing diagnostic and generative AI models across eight clinical datasets, improving diagnostic reasoning, resident concordance, and evidence generation. Targeted synthetic augmentation guided by subgroup performance gaps further enhances model performance, particularly for Asian patients.

By Suyang Xi, Songtao Hu, Shansong Wang, Mojtaba Safari, Luke del Balzo, Ehsan Ul Karim, Mingzhe Hu, Kuo Zhang, Tonghe Wang, Ralph R. Weichselbaum, Xiaofeng Yang
arXiv Machine Learning
Jul 30

Rethinking Clinical Relevance in Chest X-ray Machine Learning: How Evaluation References Define Performance

arXiv:2607. 26333v1 Announce Type: cross Abstract: Chest X-ray (CXR) machine learning relies heavily on automated evaluation using reference standards that aim to approximate clinical judgment.

By Panagiotis Fytas, Ian Selby, Clemens Karner, Judith Babar, Simon Baker, Jake Beckford, Timothy J. Sadler, Shahab Shahipasand, Arthikkaa Thavakumar, John Li Chen, Alex Sawer, Michael Roberts, Jonathan Weir-McCall, J. H. F. Rudd, Carola-Bibiane Sch\"onlieb, Anna Korhonen, Anna Breger
arXiv AI
Aug 5

HERO: Hierarchical Evidential Reasoning Optimization for Radiology Report Generation via Reason-then-Summarize

arXiv:2601. 03321v3 Announce Type: replace-cross Abstract: Multimodal Large Language Models (MLLMs) have substantially advanced Radiology Report Generation (RRG), yet aligning them through reinforcement learning (RL) remains challenging due to heterogeneous medical supervision.

By Kun Zhao, Guodong Liu, Hui Ji, Siyuan Dai, Pan Wang, Jifeng Song, Chenghua Lin, Liang Zhan, Haoteng Tang
arXiv AI
Jun 16

XMedFusion: A Knowledge-Guided Multimodal Perception and Reasoning Framework for Autonomous Medical Systems

arXiv:2606. 14766v1 Announce Type: cross Abstract: Autonomous medical and robotic systems increasingly rely on intelligent perception and reasoning capabilities to interpret visual data and support clinical decision making.

By Hamza Riaz, Arham Haroon, Maha Baig, Muhammad Dawood Rizwan, Muhammad Naseer Bajwa, Muhammad Moazam Fraz
arXiv Machine Learning
Aug 7

Positive-Unlabeled Preference Optimization For Chest X-ray Report Generation

arXiv:2608. 05341v1 Announce Type: cross Abstract: Vision-Language Models (VLMs) for radiology report generation are typically trained on retrospective clinical reports, which suffer from omission noise: clinically present findings are left unreported due to the omission of subtle findings.

By Yuta Kobayashi, Pradyun Ramesh, Muhammad Ahmed Chaudhry, Vincent Jeanselme, Judy Wawira Gichoya, Sanmi Koyejo, Kathleen Capaccione, Shalmali Joshi
arXiv AI
6d ago

Reporting Practice Matters: The Impact of Reference Choice on Chest X-ray Report Evaluation

The study examines how differences in radiologists’ reporting styles—such as terminology, shorthand, formatting, and detail—affect the evaluation of AI-generated chest X‑ray reports. By quantifying the sensitivity of common metrics to these variations, the authors show that changes in reference reports can shift model rankings. They introduce a taxonomy of reporting variations and a rewriting method, ReRef, that preserves clinical meaning while altering style, and release a validated dataset of paired reference reports to aid future research.

By Daniel P. Jeong, Charles Q. Li, Hossein Hosseiny, Nitya M. Bhalla, Fatma Uyar Morency, Pradeep Ravikumar, Zachary C. Lipton, Michael Oberst
Hugging Face Trending Papers
Jul 21

DobicVLM: Aligning Chest X-Ray Report Generation with Clinically-Grounded Programmatic Rewards via Group Relative Policy Optimization

Medical imaging is a cornerstone of diagnostics, yet automated chest X-ray report generation struggles with structural adherence, anatomical completeness, and semantic faithfulness. We introduce DobicVLM, a vision-language model combining supervised fine-tuning on MedGemma-4B with Group Relative Policy Optimization (GRPO) and clinically-grounded programmatic rewards.