arXiv Machine Learning

A spectral audit framework reveals task-dependent aperiodic reliance across EEG and ECG deep learning

arXiv:2606. 08583v1 Announce Type: new Abstract: Deep learning on physiological time series is interpreted through domain-specific features -- oscillatory rhythms in EEG, morphological complexes in ECG -- yet these signals sit atop a broadband aperiodic 1/f-like envelope that covaries with arousal, age, and pathology.

arXiv AI
3d ago

NeuroAtlas: Benchmarking Foundation Models for Clinical EEG and Brain-Computer Interfaces

NeuroAtlas is the largest EEG benchmark to date, comprising 42 datasets and 260,000 hours of clinical EEG data across epilepsy, sleep medicine, brain age estimation, and brain‑computer interfaces. The study evaluates foundation models (FMs) for EEG against supervised baselines and generic time‑series FMs, finding that EEG‑specific FMs do not consistently outperform generic ones. It also demonstrates that standard machine‑learning metrics are inadequate for clinical relevance, advocating for task‑specific measures such as event‑level decision quality, hypnogram features, and brain‑age gap.

By Konstantinos Kontras, Trui Osselaer, Stylianos G. Mouslech, Angeliki-Ilektra Karaiskou, Guido Gagliardi, Thomas Strypsteen, Mohammad Hossein Badiei, Anku Rani, Maarten Vanmarcke, Miguel Bhagubai, Chanakya Ekbote, Jaedong Hwang, Christos Chatzichristos, Paul Pu Liang, Maarten De Vos
arXiv AI
Jul 28

Neonatal Hypoxic-ischaemic Encephalopathy Classification from the EEG and HRV Signals Using a Conformer based Masked Autoencoder

arXiv:2607. 23554v1 Announce Type: cross Abstract: In this paper, we propose the MAEConformer, a novel self-supervised learning framework that combines the Conformer architecture with the Masked Autoencoder (MAE) paradigm for large-scale representation learning from unlabelled electroencephalography (EEG) and heart rate variability (HRV) signals.

By Shuwen Yu, William P Marnane, Geraldine B. Boylan, Gordon Lightbody
arXiv AI
Jul 7

Test-Time Adaptation for EEG Foundation Models: A Systematic Study under Real-World Distribution Shifts

arXiv:2604. 16926v2 Announce Type: replace-cross Abstract: Electroencephalography (EEG) foundation models have shown strong potential for learning generalizable representations from large-scale neural data, yet their clinical deployment is hindered by distribution shifts across clinical settings, devices, and populations.

By Gabriel Jason Lee, Jathurshan Pradeepkumar, Jimeng Sun
arXiv Machine Learning
Aug 4

Rethinking PPG-based Sleep Staging: Datasets, Metrics, and Benchmarks

arXiv:2608. 00943v1 Announce Type: cross Abstract: Automated sleep staging assigns discrete stage labels to successive time epochs throughout an overnight recording; conventionally each window spans at least 30 seconds, reflecting the minimum temporal resolution of the clinical scoring standard.

By Shuntian Zheng, Jiawei Wang, Cong Fu, Huan Yu, Chen Chen, Yu Guan, Sai Gu
arXiv AI
Sep 15

EEG-Xplain: Decoding Neural Black-Boxes of EEG Foundation Models

EEG-Xplain introduces a unified attribution framework to interpret EEG foundation models such as BIOT, LaBraM, and EEGMamba. The framework combines gradient, perturbation, and activation-based methods to analyze model behavior across spatial, temporal, and frequency dimensions, identifying critical channels, decision-relevant signal segments, and contributions of canonical EEG rhythms. It evaluates explanation reliability with population-level metrics and uses large language models to convert structured attributions into natural-language reports, demonstrating consistency with known neurophysiological markers on benchmark datasets.

By Hansong Ma, Junxiao Wang
arXiv Machine Learning
Aug 31

Leveraging a Foundation Model for the EEG-Based Diagnosis of Alzheimer's Disease

The paper presents a diagnostic framework for Alzheimer’s disease that uses the Large Brain Model (LaBraM), a foundation model pretrained on over 2,500 hours of EEG data, to generate high‑dimensional latent embeddings. These embeddings are fed into a non‑linear Random Forest classifier, achieving an ROC‑AUC of 89.36% ± 3.49%, PR AUC of 81.45% ± 4.43%, and Balanced Accuracy of 82.44% ± 4.34% in a subject‑independent 5‑fold cross‑validation setting, using only 8‑second EEG segments. Post‑hoc occlusion and neurophysiological alignment analyses confirm that the model captures clinically validated biomarkers such as occipital‑frontal Alpha and Theta rhythm degradation and correlates with cognitive performance and clinical severity.

By Maggie Lin, Chung-Lin Hou, Tzyy-Ping Jung