The paper presents a distribution‑free risk‑control framework that provides organ‑specific recall guarantees for frozen multi‑organ CT segmentation models. It calibrates per‑organ thresholds for an AMOS‑trained nnU‑Net, audits its transfer to RAOS, and estimates local re‑certification costs using case‑level voxel false‑negative rates. The study compares Risk‑Controlling Prediction Sets (RCPS) and Conformal Risk Control (CRC), noting that RCPS offers high‑probability control of population‑mean risk while CRC provides weaker expectation control, and evaluates the effectiveness of the Waudby–Smith–Ramdas betting bound versus Hoeffding–Bentkus bounds for re‑certification.
"whyItMatters":"The work demonstrates how to maintain organ‑level recall guarantees when deploying segmentation models across different clinical domains, highlighting the trade‑offs between threshold conservatism and re‑certification effort."
By Souraj Adhikary, Negar Chabi, Andre Mastmeyer
arXiv:2606. 20115v1 Announce Type: new Abstract: Conformal risk control (CRC) provides distribution-free guarantees on segmentation quality by calibrating a prediction-set threshold on held-out data.
By Nafis Fuad Shahid
arXiv:2606. 20115v3 Announce Type: replace Abstract: Conformal risk control (CRC) provides distribution-free segmentation guarantees by calibrating a prediction-set threshold on held-out data.
By Nafis Fuad Shahid
arXiv:2609.38112v1 Announce Type: cross
Abstract: Many applications of black-box predictive models require controlling task-relevant error rates, such as missed lesion pixels in segmentation or misse...
By Bruno Marcondes e Resende, Helton Graziadei, Thiago Rodrigo Ramos, Rafael Izbicki
arXiv:2607. 22727v1 Announce Type: cross Abstract: Medical image segmentation models often report high benchmark accuracy under ideal imaging conditions, yet their failures under clinical degradation can be quiet: sensor noise, patient motion, low- resolution acquisition, and contrast variability may all alter model behavior without producing an obvious warning.
By Pranav Kaliaperumal, Manisha Kaliaperumal
arXiv:2606. 19300v1 Announce Type: cross Abstract: Glioma segmentation in multiparametric MRI is a critical component of treatment planning.
By Xin Ci Wong, Duygu Sarikaya, Kieran Zucker, Marc De Kamps, Nishant Ravikumar
The paper introduces BiCC, a bidirectional connected-component loss that pairs annotation- and prediction-derived partitions to score predicted components on their own scale. By deriving instances from predictions, BiCC directly penalizes false-positive components regardless of size, allowing a balance parameter to control the lesion-wise precision–recall trade-off. Across five datasets, BiCC outperforms existing instance-aware losses such as CC-DiceCE and blob loss in lesion-wise F1, and improves over DiceCE on multiple datasets.
By Luc Bouteille, Frederic Jonske, Jens Kleesiek, Alexander Jaus
arXiv:2606. 15153v1 Announce Type: new Abstract: Selective prediction with distribution-free risk control promises that, with confidence 1-delta over the calibration draw, the error rate of accepted inputs stays below a user budget alpha.
By Jingwen Zhou, Mingzhe Wang
The paper introduces RouteCert, a method for ensuring risk control in multimodal systems that acquire inputs adaptively. It shows that conditional calibration can remain valid even when the acquisition policy determines the calibration group, and provides two finite‑sample constructions: threshold‑free routing with terminal‑pattern calibration and simultaneous validation of policy‑pattern pairs. Experiments on a clinical ECG task and masked multimodal benchmarks demonstrate that RouteCert achieves low disagreement rates and competitive answered fractions while validating each acquisition stage separately.
By Melika Baghi
The paper introduces DAMM‑Net++, a 2.5D neural network for thoracic organ‑at‑risk and target volume segmentation that tackles inter‑slice surface incoherence, small low‑contrast target failure, and lack of per‑case reliability signals. Its core is an anatomy‑change‑aware bidirectional selective state‑space memory that propagates context across axial slices, complemented by a boundary‑aware decoder and an uncertainty head for calibrated per‑voxel confidence. Evaluations on 2,146 patients, an external cohort, and a reader study show high Dice scores (0.955), low HD95 (3.78 mm), significant time savings (75‑80 %) for clinicians, and improved junior‑reader performance, with the system fully integrated into a clinical workflow.
By Galib Ahmed, Istiak Ahmed, Aritra Islam Saswato, Asib Mostakim Fony, Kazi Shahriar Sanjid, Md. Tanzim Hossain, Md. Anwarul Islam, Md. Nishan Khan, Md. Misbah Khan, Labiba Faiza Karim, Jobaer Rahman, S M Hasibul Hoque, Rahnuma Shahrin Rista, Kamruzzaman Rumman, Md Arifur Rahman, Syed Md. Akram Hussain, Mohammad Ashrafuzzaman Khan, M. Monir Uddin
arXiv:2607. 25164v1 Announce Type: cross Abstract: A CT examination captures multiple organs, but many biomedical questions concern abnormalities, prognosis, or longitudinal change in a specific organ.
By Zhixuan Ge, Anqi Li, Sadeer Al-Kindi, Hanwen Xu, Wei Qiu
arXiv:2606. 08517v1 Announce Type: new Abstract: Selective predictors answer on confident inputs and abstain elsewhere; deploying one safely needs a single finite-sample certificate that simultaneously upper-bounds the selected risk, lower-bounds the acceptance probability $\pacc$ above a floor $\pmin$, and lower-bounds the deployment utility.
By Xiaoli Yu, Jiamiao Liu