arXiv:2606. 09605v1 Announce Type: new Abstract: Foundation models offer a promising route to compress multi-modal physiological signals into compact representations of human health, with broad applications across sleep medicine, cardiology, neurology and other healthcare domains.
By Jonathan F. Carter, Lionel Tarassenko
SleepFM-2 is a foundation model trained on 282,511 polysomnography recordings, covering over two million hours of multimodal sleep physiology. It outperforms its predecessor in disease prediction, sleep scoring, and event detection, and its representation improves performance across diverse tasks—including wearable sensing, subjective sleep reports, and transfer to other EEG modalities. When combined with age, sex, and BMI, the model meets stringent discrimination criteria for 215 EHR phenotypes, adding reproducible information beyond demographics for 155 of them.
By Rahul Thapa, Christopher Sun, William Theodor Lehn-Schioler, Sophia Claire Kivelson, Umaer Hanif, Hyatt Moore IV, Harrison G. Zhang, Hafsa Ahmed, Marcus Dige, Niels R. Lorenzen, Elisabeth Roxane M. Heremans, Adrien Specht, Ulysse Gimenez, Robin Guillard, Andreas Brink-Kjaer, James Zou, Emmanuel Mignot
arXiv:2411. 15240v5 Announce Type: replace-cross Abstract: Wearable movement data is collected by nearly all commercially available smartwatches and is a valuable resource for mental health research, reflecting fine-grained temporal behavioral trends.
By Franklin Y. Ruan, Aiwei Zhang, Jenny Y. Oh, SouYoung Jin, Nicholas C. Jacobson
arXiv:2608. 07759v1 Announce Type: cross Abstract: Cardiovascular AI models can classify clean elec- trocardiogram (ECG) signals, but real wearable signals change because of motion, breathing, posture, sensor contact, and true clinical deterioration.
By Farouk Ganiyu Adewumi, Timothy Oladunni, Rochak Ghimire, Kosisochukwu Ogbuanya, Sanaa Reeves, Sandy Akoy
arXiv:2607. 09749v1 Announce Type: cross Abstract: Foundation models have recently emerged as a powerful paradigm for learning transferable representations from large scale biomedical data, yet existing approaches for physiological waveforms primarily optimize reconstruction or forecasting objectives that do not explicitly preserve clinically meaningful waveform morphology.
By Saiyang Feng, Yuanyun Zhang, Shi Li
arXiv:2608. 12944v1 Announce Type: new Abstract: Electrocardiography (ECG), photoplethysmography (PPG), and phonocardiography (PCG) provide complementary views of the same cardiac cycle, yet existing cardiac foundation models are trained for a single sensing modality, leaving the shared physiology across sensors unexploited.
By Hamza Shafiq, Hung Manh Pham, Bin Zhu, Pan Zhou, Jun Hu, Aaqib Saeed
SOTER is a generative foundation model designed for wearable physiological time‑series data. It integrates cross‑channel coupling, spectrum‑guided expert specialization, and continuous‑time latent evolution, using a spatial feature‑aware backbone, a PSD‑guided mixture‑of‑experts layer, and a neural controlled differential equation decoder. Trained on 226 billion time points from five public datasets, SOTER outperforms baselines in zero‑shot forecasting, classification, and imputation across six benchmarks, and remains robust to additive noise.
By Fangke Chen, Sirry Chen, Wei Chen, Zhongyu Wei
arXiv:2605. 22759v2 Announce Type: replace Abstract: While ubiquitous wearable sensors capture a wealth of behavioral and physiological information, effectively transforming these signals into personalized health insights is challenging.
By Girish Narayanswamy, Maxwell A. Xu, A. Ali Heydari, Samy Abdel-Ghaffar, Marius Guerard, Kara Vaillancourt, Zhihan Zhang, Jake Garrison, Levi Albuquerque, Dimitris Spathis, Hong Yu, Hamid Palangi, Xuhai "Orson" Xu, David G. T. Barrett, Joseph Breda, Jed McGiffin, Yubin Kim, Yuwei Zhang, Naghmeh Rezaei, Samuel Solomon, Karan Ahuja, Tim Althoff, Jake Sunshine, Ming-Zher Poh, Benjamin Yetton, Ari Winbush, Nicholas B. Allen, James M. Rehg, Isaac Galatzer-Levy, Yun Liu, John Hernandez, Anupam Pathak, Conor Heneghan, Yuzhe Yang, Ahmed A. Metwally, Pushmeet Kohli, Mark Malhotra, Shwetak Patel, Xin Liu, Daniel McDuff
BEAT-Net is a supervised biomimetic framework for ECG diagnosis that incorporates QRS-centered tokenization and a hierarchical architecture mirroring a cardiologist’s workflow. It processes heartbeat sequences through morphological, spatial, temporal, and transformer-based stages, achieving an AUC of 0.924 on large benchmarks while using only 0.7 million parameters. The model outperforms the 39.5‑million‑parameter HeartLang foundation model on morphological form classification and demonstrates superior cross‑dataset generalization with only 35% of the training data.
By Runze Ma, Haonan Lyu, Shunbo Jia, Qiang Yang, Muzi Xu, Jiaqi Zhang, Zihe Luo, Caizhi Liao
arXiv:2607. 16235v1 Announce Type: cross Abstract: Mobile and wearable devices offer an unprecedented opportunity for continuous, passive health monitoring and active health coaching.
By Narayan Schuetz, Yuze Bai, Lianggang Pan, Edgar Eggert, Favour Nerrise, Juan Delgado-SanMartin, Max Rosenblattl, Milana Gurbanova, Mohammad Asadi, Anders Johnson, Paul Schmiedmayer, Dennis Wang, Allan Lawrie, Daniel Seung Kim, Xin Liu, Akshay Paruchuri, Ehsan Adeli, Euan Ashley, Kelly W. Zhang
arXiv:2608. 03597v1 Announce Type: new Abstract: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with increased risks of stroke, heart failure, and mortality.
By Amirhossein Taleshinosrati, Yangyang Wang, Atitaya Phoemsuk, Vahid Abolghasemi, Naser Hossein Motlagh, Sadasivan Puthusserypady, Daniel Teichmann, Abdolrahman Peimankar
The study compares six state‑of‑the‑art sleep‑staging foundation models on the MESA polysomnography dataset under three signal conditions: EEG only, ECG only, and EEG+ECG. Results show that EEG alone yields the highest accuracy (BIOT macro‑F1 = 0.7237), while switching to ECG alone incurs a consistent accuracy loss of about 0.35 macro‑F1 and reduces data rate to one‑third. Adding ECG to EEG offers little benefit for most models, indicating that EEG carries most of the sleep‑staging signal and that wearable‑compatible ECG alone is a viable but less accurate alternative.
By Hassan Mehdi, Riku Klen, Ayse Kosal Bulbul, Suzanne Timmons, Abdulhamit Subasi, Wei Chen, Zou Zhu, Muhammad Irfan