CoMMa is a decentralized large language model (LLM) agent framework designed for oncology decision support. It allows specialists to work on partitioned clinical data streams, enforcing data decentralization and enhancing role specialization through agent-specific fine‑tuning. The framework introduces a contribution‑aware aggregation mechanism that replaces stochastic reasoning with deterministic embedding projections, enabling explicit credit assignment and a stable, interpretable decision pathway.
arXiv:2608.22176v1 Announce Type: new Abstract: Large Language Models (LLMs) are increasingly applied to clinical prediction tasks such as in-hospital mortality and readmission from electronic health...
arXiv:2608.27856v1 Announce Type: new Abstract: Recent advances in large language models are enabling autonomous clinical agents to perform increasingly complex electronic health record (EHR) modelin...
arXiv:2608. 11420v1 Announce Type: new Abstract: Medical diagnostic reasoning is a high-impact use case for LLMs that carries significant implications for the health and wellbeing of users.
The paper introduces MIMIC-DOS, a dataset derived from MIMIC-IV that focuses on ICU cases where patient symptoms and medical signs are discordant. It presents CARE, a privacy‑compliant multi‑stage agentic reasoning framework that uses a proprietary LLM to generate structured categories and transitions, while a local LLM performs evidence acquisition and decision‑making. In retrospective evaluations on MIMIC‑DOS, CARE outperforms other LLMs and agentic workflows, demonstrating stronger handling of conflicting clinical evidence while preserving patient privacy.
The paper introduces MACD, a Multi-Agent Clinical Diagnosis framework that enables large language models to self‑learn clinical knowledge through a multi‑agent pipeline of summarization, refinement, and application. MACD is extended into a human‑AI collaborative workflow where multiple diagnostician agents consult iteratively, guided by a judge agent and human oversight. Evaluation on the MIMIC‑MACD cohort shows significant gains in diagnostic accuracy—an average 11.6 percentage‑point improvement over authoritative knowledge for open‑weight LLMs and an 18.3‑percentage‑point boost over physician‑only diagnosis in text‑only vignettes.
arXiv:2608.28662v1 Announce Type: new Abstract: Fracture detection and its clinical interpretability see notable improvements when deep vision models are integrated with agentic AI architectures. Whi...
arXiv:2608. 13476v1 Announce Type: new Abstract: We present Multi-Agent Reasoning and Coordination (MARC), an open-source framework that replaces monolithic LLM prompting with deterministic multi-agent orchestration for clinical reasoning.
arXiv:2603. 01131v3 Announce Type: replace-cross Abstract: Clinical diagnosis is a gradual process of evidence integration, in which physicians move from symptoms and medical history to examinations, competing hypotheses, disease relations, and treatment decisions.
arXiv:2606. 01094v1 Announce Type: new Abstract: Clinical order generation serves as a critical bridge between clinical decision-making and real-world practice, translating medical decisions into concrete and executable orders.
arXiv:2608.21948v1 Announce Type: new Abstract: Complex clinical reasoning requires models to update diagnostic hypotheses as new evidence emerges and to coordinate different medical specialities und...
arXiv:2606. 31085v1 Announce Type: new Abstract: Drug-drug interaction (DDI) prediction is essential for medication safety, yet it requires reasoning over heterogeneous biomedical evidence whose relevance changes across interaction mechanisms.
arXiv:2607. 15314v1 Announce Type: new Abstract: Healthcare spans high-stakes communication, expert reasoning, and workflow execution, yet specialized LLMs that cover these use cases together remain limited.