The paper introduces a modular agentic-AI platform that transforms heterogeneous CMC process-development documents into a dual-layer knowledge graph. The base layer creates a lexical Document‑Section‑Chunk hierarchy, while the intelligence layer extracts ontology‑aligned entities and links cross‑document concepts, all anchored by provenance. LLM agents navigate these layers to answer queries, and a novel three‑tier evaluation protocol demonstrates high retrieval‑augmented generation performance on proprietary data from a Sanofi program.
By Reza Amirmoshiri, Faryad Sahneh, Yasser Jangjou
arXiv:2608. 06713v1 Announce Type: new Abstract: Biomedical knowledge graphs (KGs) accelerate drug discovery, but standard pipelines assume query molecules already exist as graph entities, leaving unregistered molecules disconnected.
By Yiming Zhang, Hikaru Shindo, Shuan Chen, Kaushalya Madhawa, Jun Jin Choong, Yuna Oikawa, Takashi Fujiwara, Keisuke Ozawa
arXiv:2609.06779v1 Announce Type: cross
Abstract: Drug repurposing aims to identify new therapeutic uses for existing compounds and, compared with de novo drug discovery, offers a faster and more cos...
By Zijie Liu, Hongxuan Li, Zhen Tan, Jinhao Duan, Baixiang Huang, Zunpeng Liu, Kai Shu, Tianlong Chen
arXiv:2608.30556v1 Announce Type: new
Abstract: Path-finding over knowledge graphs has become an effective way to ground LLM reasoning on multi-hop questions. However, biomedical QA introduces two di...
By Jun Hyeong Kim, Dongki Kim, Yinhua Piao, Sung Ju Hwang
The paper introduces a novel LLM‑driven multi‑agent pipeline that converts relational databases into graph databases by standardizing table and column names and iteratively refining the graph schema through ETL, Analyzer, and Graph agents. The resulting graph database meets accuracy, groundedness, and faithfulness criteria and shows significant performance gains, achieving 85.6% Q&A accuracy—12.12% higher than an SQL agent on PostgreSQL—and reducing latency by roughly threefold on a BFSI dataset. This demonstrates an efficient, automated method for transforming tabular data into a more intuitive and faster‑executing graph format.
By Dinh-Khanh Pham, Quy-Anh Dang, Lam Mai Thanh, Khanh Bui, Truong-Son Hy
arXiv:2610.14465v1 Announce Type: cross
Abstract: Structured knowledge retrieval acquires task-relevant evidence from structured knowledge sources for downstream tasks. Existing methods rely on uncon...
By Zhisheng Qi, Haoyu Han, Jiaxi Li, Bing He, Huiyuan Chen, Franck Dernoncourt, Ryan A. Rossi, Mahantesh M. Halappanavar, Jin Lu, Yu Zhang, Tianming Liu, Yu Wang