The paper benchmarks six long‑tail loss functions—cross‑entropy, weighted CE, class‑balanced loss, focal loss, LDAM, and logit‑adjusted softmax—across three single‑cell foundation model architectures (scGPT, scBERT, Geneformer) and three datasets (Multiple Sclerosis, Zheng68K, human Pancreas). It shows that overall accuracy masks systematic failures on rare, disease‑relevant cell types, with a consistent gap between overall accuracy, Macro‑F1, and rare‑class recall under plain cross‑entropy. The study identifies two distinct regimes of rare‑class failure, predicts reweighting efficacy by absolute training‑set size, and finds class‑balanced loss and LDAM to be the most reliable across all settings.
By Zeyu Dong, Jiahui Zhong
The paper introduces AdaConRed, a label‑free post‑conformal decision rule that transforms ambiguous conformal prediction sets into single class assignments for medical image classification. It employs a five‑stage pipeline—vision‑language generative augmentation, a frozen DermFoundation encoder, a lightweight MLP classifier, an entropy‑modulated margin‑aware nonconformity score, and a reassignment step for transitional samples—to improve accuracy on OSCC and ISIC benchmarks. Results show notable gains in malignant class accuracy while maintaining overall performance.
By Saibal Ghosh, Samarup Bhattacharya, Sanjoy Kumar Saha, Umapada Pal, Tapabrata Chakraborti
arXiv:2401.03580v2 Announce Type: replace-cross
Abstract: We study hyperparameter optimization (HPO) from a numerical-optimization perspective and propose a multi-objective, damped Gauss--Newton sear...
By Qinwu Xu
arXiv:2606. 26053v1 Announce Type: cross Abstract: Synthetic data augmentation is widely used to mitigate class imbalance, but its theoretical effects on score-based classification remain poorly understood.
By Zhengchi Ma, Pengfei Lyu, Anru R. Zhang
arXiv:2607. 16802v1 Announce Type: new Abstract: Deep survival models are evaluated almost exclusively by the concordance index (C-index), yet they are commonly trained using likelihood objectives such as the Cox partial likelihood, discrete-time negative log-likelihood, and DeepHit likelihood.
By Meixu Chen, Kai Wang, Jing Wang
arXiv:2607. 18088v1 Announce Type: new Abstract: Standard evaluation of many recognition systems contains distribution shift by construction, since benchmarks place disjoint conditions in the training and test splits.
By Weijia Han, Lisha Qu