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Semantic-Aware Subgraph State Space Model for WSI Classification in Histopathology

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The paper introduces the Semantic-Aware Subgraph State Space Model (SASG-SSM) for classifying whole slide images in histopathology. It groups spatially connected patches into semantic subgraphs that preserve internal spatial organization, then uses a graph neural network encoder combined with a Mamba-based state space encoder to integrate local and global contextual information. Experiments on four WSI subtyping datasets show consistent performance gains over state‑of‑the‑art methods, with additional robustness in small‑cohort and few‑shot scenarios.

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arXiv Computer Vision
Sep 4

Semantic-Aware Subgraph State Space Model for WSI Classification in Histopathology

The paper introduces the Semantic-Aware Subgraph State Space Model (SASG-SSM) for classifying whole slide images (WSIs) in histopathology. It groups spatially connected patches into semantic-aware subgraphs that preserve internal spatial organization, then uses a graph neural network encoder combined with a Mamba-based state space encoder to capture both local and global contextual information. Experiments on four WSI subtyping datasets show consistent performance gains over state‑of‑the‑art methods, with additional robustness in small‑cohort and few‑shot scenarios.

By Feixing Chen, Hao Lu, Lin Luo, Yan Xu
arXiv AI
Sep 15

End-to-End Cell Detection via Instance-aware Graph Modeling

The paper introduces an end‑to‑end framework for detecting and classifying cells in pathology images by jointly modeling visual features and instance‑level interactions. It employs a dynamic graph construction module that builds cell graphs from learnable queries and an instance‑aware graph network that filters and reorganizes features, integrating appearance and relational evidence. Experiments on multiple staining protocols show the method surpasses existing approaches in both detection and classification accuracy.

By Ruochen Liu, Yalin Zheng, Jingxin Liu, Jianfeng Zhang, Shoujun Huang, Dexing Kong, Haofeng Li, Wei Lou
arXiv Computer Vision
Sep 25

Context-aware Skin Cancer Epithelial Cell Classification with Scalable Graph Transformers

The paper introduces scalable Graph Transformers for classifying healthy versus tumor epithelial cells in whole-slide images of cutaneous squamous cell carcinoma. By constructing a full‑WSI cell graph and incorporating morphological, texture, and neighboring cell class features, the proposed SGFormer and DIFFormer models outperform traditional image‑based methods, achieving balanced accuracies above 85% on single‑WSI tests and 83.6% on multi‑WSI evaluations. The study demonstrates that preserving tissue‑level context through graph representations improves classification of morphologically similar cell types.

By Lucas Sanc\'er\'e, No\'emie Moreau, Katarzyna Bozek