arXiv:2606. 10543v1 Announce Type: cross Abstract: Designing functional biological sequences requires navigating vast discrete spaces under strict evolutionary and biophysical constraints.
By Yogesh Verma, Dani Korpela, Harri L\"ahdesm\"aki, Vikas Garg
arXiv:2601. 14430v2 Announce Type: replace-cross Abstract: Controlling generative models is computationally expensive.
By Peter Potaptchik, Adhi Saravanan, Abbas Mammadov, Alvaro Prat, Michael S. Albergo, Yee Whye Teh
arXiv:2509. 26405v2 Announce Type: replace Abstract: We introduce InVirtuoGen, a discrete flow generative model for fragmented SMILES for de novo and fragment-constrained generation, and target-property/lead optimization of small molecules.
By Benno Kaech, Luis Wyss, Karsten Borgwardt, Gianvito Grasso
arXiv:2604. 27147v3 Announce Type: replace-cross Abstract: In generative modeling, we often wish to produce samples that maximize a user-specified reward such as aesthetic quality or alignment with human preferences, a problem known as \textit{guidance}.
By Jerry Y. Huang, Justin Lin, Sheel Shah, Kartik Nair, Nicholas M. Boffi
arXiv:2607. 23408v1 Announce Type: new Abstract: Expensive black-box optimization is ubiquitous in science and engineering, where function evaluations are costly and the evaluation budget is limited.
By Jintao He, Huixiang Zhen, Wenyin Gong
arXiv:2607. 18755v1 Announce Type: new Abstract: Flow-based models have established state-of-the-art performance in generative modeling across domains, but are hard to interpret due to their complex latent embeddings.
By Anirudh jain, Sakshi Varshney, Samuel Kaski, Vikas Garg