arXiv AI By Hamed Javidi, Alex Zajichek, Hakan Doga, Laxmi Parida, Filippo Utro, Peter J. Mazzone

Quantum Kernel Estimation for the Discovery of Early Lung Cancer Detection

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arXiv:2608. 19304v1 Announce Type: cross Abstract: Lung cancer screening with low-dose chest computed tomography reduces mortality, but its impact is limited by uptake, adherence, and management challenges.

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arXiv Machine Learning
Jul 14

$\mathtt{Q^2SAR}$: overcoming classical bottlenecks in drug discovery via quantum multiple kernel learning

arXiv:2607. 11701v1 Announce Type: cross Abstract: Quantitative Structure-Activity Relationship ($\mathtt{QSAR}$) modeling is a foundational computational methodology in early-stage drug discovery, heavily relied upon for predicting compound toxicity, bioavailability, and therapeutic potential.

By Mariano Caruso, Daniel Ruiz, Alejandro Giraldo, Guido Bellomo
arXiv Machine Learning
Sep 14

Classical and quantum kernel fusion for two-sample testing

The paper introduces MMD-FUSE, a two-sample test that remains effective on small datasets by fusing classical and quantum kernels. By combining the inductive biases of classical kernels with the expressive power of quantum kernels, the hybrid approach achieves higher test power, especially for small, high‑dimensional data. Experiments on synthetic and real clinical datasets confirm that the method consistently outperforms purely classical counterparts and adapts robustly to varied data characteristics.

By Yu Terada, Yugo Ogio, Ken Arai, Hiroyuki Tezuka, Yu Tanaka
arXiv Machine Learning
Jun 15

Hybrid Classical-Quantum (HCQ) Alzheimer's Classification via Supervised $\beta$-VAE and Quantum Kernels

arXiv:2606. 14194v1 Announce Type: cross Abstract: This paper presents a two-stage Hybrid Classical-Quantum (HCQ) pipeline for binary Alzheimer's disease (AD) classification from 3D T1-weighted structural MRI volumes, where the classical and quantum components are designed to complement each other rather than operate independently.

By Tia Tiwari, Vamshi Krishna Kancharla, Neelam Sinha
arXiv Statistics ML
Sep 18

Improving Sample Efficiency in Peptide-HLA Binding Prediction with Hybrid Quantum-Classical Neural Networks

The paper introduces a hybrid quantum-classical neural network (HQNN) for predicting peptide-HLA binding, a key step in personalized cancer immunotherapy. HQNN combines biological feature encoding, quantum feature extractors, and a quantum-enhanced classifier, outperforming a classical CNN baseline on two HLA alleles across all training sizes, especially when data are scarce. Ablation studies and noise-aware simulations confirm the benefits of the quantum components and the robustness of the approach under realistic hardware noise.

By Chenyan Jia, Cong Guo, Siyue Chen, Pengpeng Ye, Xiaochun Chen