arXiv AI

Geometric and Quantum Kernel Methods for Predicting Skeletal Muscle Outcomes in chronic obstructive pulmonary disease

arXiv:2601. 00921v3 Announce Type: replace-cross Abstract: Chronic obstructive pulmonary disease (COPD) affects hundreds of millions of people worldwide, and skeletal-muscle dysfunction is clinically important.

arXiv Machine Learning
Sep 14

Classical and quantum kernel fusion for two-sample testing

The paper introduces MMD-FUSE, a two-sample test that remains effective on small datasets by fusing classical and quantum kernels. By combining the inductive biases of classical kernels with the expressive power of quantum kernels, the hybrid approach achieves higher test power, especially for small, high‑dimensional data. Experiments on synthetic and real clinical datasets confirm that the method consistently outperforms purely classical counterparts and adapts robustly to varied data characteristics.

By Yu Terada, Yugo Ogio, Ken Arai, Hiroyuki Tezuka, Yu Tanaka
arXiv Machine Learning
Jul 13

Is data-efficient learning feasible with quantum models?

arXiv:2508. 19437v2 Announce Type: replace-cross Abstract: The importance of analyzing nontrivial datasets when testing quantum machine learning (QML) models is becoming increasingly prominent in literature, yet a cohesive framework for understanding dataset characteristics remains elusive.

By Alona Sakhnenko, Christian B. Mendl, Jeanette M. Lorenz
arXiv Machine Learning
Jul 14

$\mathtt{Q^2SAR}$: overcoming classical bottlenecks in drug discovery via quantum multiple kernel learning

arXiv:2607. 11701v1 Announce Type: cross Abstract: Quantitative Structure-Activity Relationship ($\mathtt{QSAR}$) modeling is a foundational computational methodology in early-stage drug discovery, heavily relied upon for predicting compound toxicity, bioavailability, and therapeutic potential.

By Mariano Caruso, Daniel Ruiz, Alejandro Giraldo, Guido Bellomo
arXiv Machine Learning
Jul 23

A Multiclass Quantum Aligned Centroid Kernel

arXiv:2607. 19782v1 Announce Type: cross Abstract: Kernel methods are powerful tools in machine learning but commonly used full-Gram kernels face three key limitations: (1) quadratic scaling with training set size; (2) the use of fixed, non-trainable kernels; and (3) the absence of an intrinsic formulation for multiclass classification.

By Kilian Tscharke, Pascal Debus
arXiv Machine Learning
Jun 15

Hybrid Classical-Quantum (HCQ) Alzheimer's Classification via Supervised $\beta$-VAE and Quantum Kernels

arXiv:2606. 14194v1 Announce Type: cross Abstract: This paper presents a two-stage Hybrid Classical-Quantum (HCQ) pipeline for binary Alzheimer's disease (AD) classification from 3D T1-weighted structural MRI volumes, where the classical and quantum components are designed to complement each other rather than operate independently.

By Tia Tiwari, Vamshi Krishna Kancharla, Neelam Sinha
arXiv Machine Learning
Jul 27

Parameterized Quantum Circuits as Feature Maps: Representation Quality and Readout Effects in Multispectral Land-Cover Classification

arXiv:2604. 26675v2 Announce Type: replace-cross Abstract: We investigate variational quantum classifiers (VQCs) for land-cover classification from multispectral satellite imagery, adopting a feature-map perspective in which the quantum circuit defines a nonlinear data embedding while the readout determines how this representation is exploited.

By Ralntion Komini, Aikaterini Mandilara, Georgios Maragkopoulos, Dimitris Syvridis
arXiv Machine Learning
Jun 30

Exploring the Effects of Entanglement on Quantum Machine Learning of Pathogen Epitope-Receptor Binding

arXiv:2606. 28655v1 Announce Type: cross Abstract: Parameterized quantum circuits (PQCs) provide a flexible substrate for hybrid quantum machine learning (QML), but their practical value on Noisy Intermediate-Scale Quantum (NISQ) devices remains an empirical question, especially because training depth and scale can introduce optimization challenges such as barren plateaus.

By Aspen Erlandsson Brisebois, Luis Pablo Gonzalez Dominguez, Shivansi Prajapati, Zahed Khatooni, Heather L. Wilson, Connor Burbridge, Brook Byrns, Sureesh Tikoo, Christophe Pere, Steven Rayan, Gordon Broderick
arXiv Machine Learning
Sep 17

Fourier Analysis of Parametrized Interactive Quantum Classifiers

The paper derives a closed‑form expression for the reduced quantum channel of a single‑qubit Interactive Quantum Classifier (IQC), revealing that Hamiltonian parameters directly control the constant, sine, and cosine components of the classifier output. This Fourier interpretation motivates a generalized family of Hamiltonian encodings, including matrix‑parameterized environmental Hamiltonians that produce non‑separable Fourier structures. Numerical experiments on synthetic and real‑world datasets demonstrate that these generalized encodings improve classification performance on several nonlinear benchmarks, with a simpler four‑parameter extension achieving comparable results with fewer trainable parameters.

By F\'abio Novaes, Fernando M. de Paula Neto, Jo\~ao V. M. Cardoso
arXiv Machine Learning
1d ago

Neural Fourier Surrogates for Data Reuploading Quantum Neural Networks

The paper introduces Neural Fourier Surrogates (NFS), a stochastic classical neural network that learns coefficients over a finite Fourier series support similar to quantum neural networks (QNNs). By testing on tabular benchmark datasets, NFS demonstrates competitive classification performance against established classical baselines and data‑reuploading QNNs. The authors also compare the learned Fourier spectra of QNNs and NFS on synthetic data, positioning NFS as a natural classical baseline for evaluating QNN performance.

By Oliver Knitter, Jonathan Mei, Sang Hyub Kim, Chi Chen, Masako Yamada, Martin Roetteler