arXiv AI By Sandesh Pokhrel, Hamid Manoochehri, Beatrice S Knudsen, Tolga Tasdizen

Predicting Metastatic Risk from Primary Cancer Tissue Architecture via Distance-Aware Spatial Modeling

Read the original on arXiv AI →

The Flow has not summarised this story yet — read it at arXiv AI.

arXiv Machine Learning
Aug 26

RACR-MIL: Rank-aware contextual reasoning for weakly supervised grading of squamous cell carcinoma using whole slide images

RACR-MIL is a weakly‑supervised method for grading squamous cell carcinoma (SCC) from whole‑slide images, using an attention‑based multiple‑instance learning framework. It introduces a hybrid WSI graph to capture local tissue context and non‑local phenotypic dependencies, and applies rank‑ordering constraints on attention to prioritize higher‑grade tumor regions, mirroring pathologists’ diagnostic reasoning. The approach achieves state‑of‑the‑art performance, improving SCC grading accuracy by 3–9% over existing methods and up to 10% in tumor localization, and a pilot study showed pathologists reported increased grading efficiency in 60% of cases.

By Anirudh Choudhary, Mosbah Aouad, Krishnakant Saboo, Angelina Hwang, Jacob Kechter, Blake Bordeaux, Puneet Bhullar, David DiCaudo, Steven Nelson, Nneka Comfere, Emma Johnson, Olayemi Sokumbi, Jason Sluzevich, Leah Swanson, Dennis Murphree, Aaron Mangold, Ravishankar Iyer
arXiv Computer Vision
4d ago

Report Supervision

The paper introduces Report Supervision (R‑Super), a framework that uses radiology reports to supervise tumor segmentation models. By incorporating loss functions that align segmentation outputs with report‑derived tumor counts, sizes, and locations, R‑Super improves detection and segmentation performance. Experiments on kidney and pancreatic tumors show up to a 15% increase in F1‑Score and DSC compared to mask‑only training, outperforming methods like CLIP and multi‑task learning.

By Pedro R. A. S. Bassia, Wenxuan Li, Jakob Wasserthal, Jieneng Chen, Xinze Zhou, Zheren Zhu, Chuntung Zhuanga, Sergio Decherchi, Andrea Cavalli, Kang Wang, Yang Yang, Alan Yuille, Zongwei Zhou