arXiv AI By Gal Sapir, Alon Diament, Adva Wolf, Doron Yaya-Stupp, Dikla Gelbard Solodkin, Dana Azouri, Anat Etzion-Fuchs, Guy Lutsker, Eran Segal, Hagai Rossman

PhenoBench: Mapping What a Deeply Phenotyped Human Cohort Can Tell Us

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arXiv AI
Oct 21

A general-purpose System One decision model for clinical records

The paper introduces Clinical System One (CS1), a 4‑billion‑parameter decision model that rapidly produces typed judgments from clinical records. Trained on 12.4 million Q&A pairs from 3.6 million patients, CS1 can answer multiple questions in a single forward pass, providing probability estimates for uncertain cases. In evaluations on 963,408 held‑out patients and 21 external datasets, CS1 outperformed larger open models and, when paired with a language‑model agent, efficiently identified trial‑eligible patients with far fewer tokens.

By Andrew Zhang, Trinh T. L. Vuong, Sophia J. Wagner, Dongmin Bang, Tong Ding, Yuchang Su, Mary Cipperman, Christina S. Chen, Judith Lefkes, Ramin Kahidi, Ming Y. Lu, Caiwei Tian, Tianhao Luo, Jingnan Ma, Rowland Pettit, Long Phi Le, Faisal Mahmood
arXiv Machine Learning
Aug 14

CoMedBench: A Multi-Source Benchmark of Synthetic Medical Data Fidelity and Downstream Utility

arXiv:2608. 12805v1 Announce Type: new Abstract: Access to clinical data is essential for developing reliable healthcare machine learning systems, but direct use of electronic health records is constrained by privacy regulation, institutional review, data-use agreements, and the risk of re-identification.

By Akanta Das, Al Amin Farhad, Mrinmoy Sarkar Anto, David Rehkopf, Ayin Vala, Tanmoy Sarkar Pias
arXiv Machine Learning
Jun 24

PORTER: Language-Grounded Event Representations for Portable Structured EHR Foundation Models

arXiv:2606. 24102v1 Announce Type: cross Abstract: Most electronic health record (EHR) foundation models encode clinical events as discrete event tokens from a fixed vocabulary and therefore cannot directly represent events containing unseen concepts or new combinations of concepts and attributes such as numeric values.

By Lin Lawrence Guo, Adam Paul Yan, Emily Vettese, Lillian Sung