arXiv:2606. 25762v1 Announce Type: new Abstract: In oncology, access to patient-level data is often restricted.
Machine-generated by The Flow from the publisher's headline and feed description — not written or checked by a human. The full article lives at arXiv Machine Learning.
A causal multi-modal AI model was developed to predict personalized chemosensitivity in breast cancer patients using routine pathology and clinical data. Trained on 9,141 patients from nine countries and validated on 1,994 patients from three countries, the model produced treatment-specific recurrence probabilities with near-perfect calibration and strong prognostic discrimination over 5- and 10-year horizons. It outperformed existing recurrence-score tests and could reduce chemotherapy prescriptions by 30% while maintaining recurrence-free rates, with predictive performance also transferring to non-breast cancers.
arXiv:2606. 05797v1 Announce Type: new Abstract: Longitudinal treatment decisions require predicting potential outcomes under future treatment sequences in the presence of time-varying confounding, heterogeneous patient dynamics, and limited domain-specific data.
arXiv:2606. 17405v1 Announce Type: new Abstract: Clinical decision support AI systems (CDSASs) must adapt to evolving patient conditions in real-time while adhering to strict safety constraints.
The paper proposes a method for estimating treatment effects using AI-generated predictions as surrogates, applied to paired before-and-after measurements for each treated individual. By comparing AI predictions before and after treatment, the approach can identify the average treatment effect on the treated under certain technical assumptions, even when clinical outcomes are never observed for treated subjects. When assumptions are questionable, the authors introduce prediction‑powered inference that corrects bias with a small set of observed outcomes, and validate the method with synthetic and cardio‑oncology data.
arXiv:2512. 08029v3 Announce Type: replace Abstract: Clinical decision-making in oncology requires predicting dynamic disease evolution, a task current static AI predictors cannot perform.
arXiv:2512.08029v4 Announce Type: replace Abstract: Clinical decision-making in oncology requires forecasting how disease evolves under treatment, yet most AI systems remain static predictors that ca...