The paper introduces MedREAL, a unified framework that aligns linguistic reasoning with spatial grounding for medical visual question answering and segmentation. MedREAL employs Seg Anchored Reasoning Pooling (SARP) to extract semantic evidence from segmentation tokens and a Reasoning-to-Visual (R2V) fusion mechanism to integrate these features into a segmentation pipeline. Using the newly created MedRAVS-13K dataset, MedREAL achieves superior performance, reporting 68.49% gIoU and 70.47% cIoU, and generates evidence masks that consistently match textual diagnoses.
By Haowen Gu, Gensheng Pei, Junzhu Mao, Qiong Wang, Mingwu Ren, Yazhou Yao
arXiv:2606. 29577v1 Announce Type: cross Abstract: Positron Emission Tomography (PET) reveals brain metabolism and is clinically central to neurodegenerative disease assessment, yet existing 3D brain foundation models treat PET as generic volumetric data, missing the structured regional metabolic information that distinguishes it from structural neuroimaging.
By Dasen Dai, Yanteng Zhang, Shuoqi Li, Yuxiang Wei, Hongjie Yu, Qingxin Zhang, Qizhen Lan, Jagath C. Rajapakse, Vince D. Calhoun
Positron Emission Tomography (PET) reveals brain metabolism and is clinically central to neurodegenerative disease assessment, yet existing 3D brain foundation models treat PET as generic volumetric data, missing the structured regional metabolic information that distinguishes it from structural neuroimaging. To address these limitations, we propose ReMAP-PET, a framework that moves beyond visual encoding by supervising a partially-tuned MedicalNet 3D ResNet-50 with brain regional standardized uptake value ratio (SUVR) profiles through joint regression and contrastive objectives, enabling the encoder to learn the metabolic semantics underlying PET modality.
arXiv:2409.16183v2 Announce Type: replace
Abstract: Radiology is a vital and complex component of modern clinical workflow and covers many tasks. Recently, vision-language (VL) foundation models in m...
By Xiaohong Liu, Guoxing Yang, Yulin Luo, Jiaji Mao, Xiang Zhang, Haibo Wang, Zhiyang He, Ming Gao, Shanghang Zhang, Jun Shen, Guangyu Wang
arXiv:2606. 28392v1 Announce Type: cross Abstract: Accurate lesion segmentation in PET/CT is critical for oncology, yet remains challenging because physiologic tracer uptake and artifacts can mimic malignant signal.
By Jiasheng Wang, Tanun Jitwatcharakomol, Piyawadee Jongpradubgiat, Simeng Zhu
arXiv:2606. 06696v1 Announce Type: cross Abstract: Vision and language models (VLMs) hold immense promise to transform biomedical imaging workflows, from detecting lesions in chest X-rays to profiling cellular features in microscopy.
By Ryan D'Cunha, Alejandro Lozano, Xiaoxiao Sun, Daniel Vela Jarquin, Min Woo Sun, Josiah Aklilu, James Burgess, Yuhui Zhang, Ryan Nayebi, Paola Avila, Robayo, Jin Ye, Ming Hu, Zhongying Deng, Junjun He, Xin Chen, Yue Yao, Robert Tibshirani, Jeffrey J. Nirschl, Serena Yeung-Levy