The paper introduces a hybrid quantum-classical neural network (HQNN) for predicting peptide-HLA binding, a key step in personalized cancer immunotherapy. HQNN combines biological feature encoding, quantum feature extractors, and a quantum-enhanced classifier, outperforming a classical CNN baseline on two HLA alleles across all training sizes, especially when data are scarce. Ablation studies and noise-aware simulations confirm the benefits of the quantum components and the robustness of the approach under realistic hardware noise.
By Chenyan Jia, Cong Guo, Siyue Chen, Pengpeng Ye, Xiaochun Chen
arXiv:2608. 04379v1 Announce Type: cross Abstract: We propose a method to optimize the correlation among convolutional neural network (CNN) features that are used as inputs to quantum neural network (QNN) to enhance image classification accuracy.
By Minseo Seong, Youngwook Kim
arXiv:2607. 21186v1 Announce Type: cross Abstract: Numerous studies have analyzed the use of hybrid quantum-classical convolutional neural networks as a promising alternative to classical deep learning.
By Guillermo Rubi\~nos Rodr\'iguez, Mart\'in Ottavianelli, Mateo Alonso, Gonzalo Bl\'azquez Gil, Boris-Stephan Rauchmann, Pablo D\'iez-Valle, Sergio Altares-L\'opez
arXiv:2510. 03389v2 Announce Type: replace-cross Abstract: Current quantum computers require algorithms that use limited resources economically.
By Jonas J\"ager, Philipp Els\"asser, Elham Torabian
arXiv:2606. 28252v1 Announce Type: cross Abstract: Early detection of oral cancer markedly improves clinical outcomes, yet specialized diagnostic tools remain scarce in low-resource settings.
By Akshay Bhagwan Sonawane, Sophie Choe, Lakshman Tamil
We propose a method to optimize the correlation among convolutional neural network (CNN) features that are used as inputs to quantum neural network (QNN) to enhance image classification accuracy. Unlike prior approaches that employ orthogonal decomposition as preprocessing, we intentionally introduce correlated features that are more physically compatible with QNN.