arXiv Machine Learning By William E. Bishop, Luuk W. Hesselink, Bernhard Englitz, Misha B. Ahrens, James E. Fitzgerald

Deep probabilistic model synthesis enables unified modeling of whole-brain neural activity across individual subjects

Read the original on arXiv Machine Learning →

arXiv:2603. 14161v2 Announce Type: replace Abstract: Many disciplines need quantitative models that synthesize experimental data across multiple instances of the same general system.

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arXiv Machine Learning
Sep 21

BrainWideBench: Benchmarking large-scale pretraining and across-animal transfer in multi-region neural recordings

BrainWideBench is a benchmark that evaluates across‑animal transfer on multi‑region neural recordings from 139 mice, covering 276 brain regions. It comprises three task suites—behavior decoding, neural activity prediction, and anatomical organization recovery—to test whether learned representations support diverse downstream objectives. The benchmark shows that while pretraining improves performance over single‑session baselines, current methods vary in transfer ability and none perform uniformly well across all suites, highlighting the challenge of developing general‑purpose neural representations.

By Alexandre Andre, Shivashriganesh P. Mahato, Vinam Arora, Keshav Balaji, Divyansha Lachi, Nanda H. Krishna, Jingyun Xiao, Yizi Zhang, Ximeng Mao, Wenrui Ma, Han Yu, International Brain Laboratory, Daniel Birman, Niccol\`o Bonacchi, Gaelle A. Chapuis, Joana A. Catarino, Felicia Davatolhagh, Mayo Faulkner, Laura Freitas-Silva, Fei Hu, Julia M. Huntenburg, Anup Khanal, In\^es Laranjeira, Petrina Lau, Guido T. Meijer, Nathaniel J. Miska, Jean-Paul Noel, Alejandro Pan-Vazquez, Georg Raiser, Cyrille Rossant, Karolina Z. Socha, Anne E. Urai, Miles J. Wells, Steven J. West, Olivier Winter, Blake Richards, Guillaume Lajoie, Cole Hurwitz, Mehdi Azabou, Matthew R. Whiteway, Liam Paninski, Eva L. Dyer
arXiv AI
3d ago

BayesNDE: Bayesian Generative Modeling for Neural Density Estimation

BayesNDE is a neural density estimator that uses Bayesian generative modeling to estimate densities without relying on invertible networks or Jacobian-determinant calculations. It constructs an adaptive proposal for each observation by inferring a sample-specific latent posterior, and then applies bridge sampling to combine proposal samples with separate posterior samples for density estimation. Experiments on synthetic datasets show improved density estimation and structure recovery, while real-world applications demonstrate better anomaly detection.

By Chenglin Li, Qiao Liu