arXiv Computation and Language By Riya Ahuja (Institute of Data Science in Biomedicine, TU Braunschweig, Braunschweig, Germany, Braunschweig Integrated Centre of Systems Biology, TU Braunschweig, Braunschweig, Germany), Tim Kacprowski (Institute of Data Science in Biomedicine, TU Braunschweig, Braunschweig, Germany, Braunschweig Integrated Centre of Systems Biology, TU Braunschweig, Braunschweig, Germany), Roya Shiasi Sardoabi (Institute of Data Science in Biomedicine, TU Braunschweig, Braunschweig, Germany, Braunschweig Integrated Centre of Systems Biology, TU Braunschweig, Braunschweig, Germany)

Configurable Semantic Chunking for Biomedical Information Extraction in Retrieval-Augmented Generation

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The paper introduces a configurable semantic chunking framework for biomedical information extraction in retrieval‑augmented generation systems. It replaces the fixed‑size chunking stage of BioMedRAG with entity‑preserving windows, trigger‑centered chunking, proposition‑first extraction, tiered trigger prioritization, and hierarchical relation resolution, while keeping the rest of the pipeline unchanged. Experiments on relation extraction benchmarks (GM‑CIHT, DDI, ChemProt) and adverse event classification (ADE) show that the hybrid configuration boosts performance on datasets with explicit relation cues, achieving 82.6% F1 on GM‑CIHT compared to 74.2% with the baseline.

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