arXiv AI
Sep 10

Building evidence-based knowledge bases from full-text literature for disease-specific biomedical reasoning

EvidenceNet is a disease‑specific dataset that transforms full‑text biomedical literature into structured evidence records and graph representations, preserving study design, provenance, and quantitative support. Using an LLM‑assisted pipeline, it extracts experimentally grounded findings, normalizes entities, scores evidence quality, and links related records via typed semantic relations. The released subsets—EvidenceNet‑HCC and EvidenceNet‑CRC—contain thousands of evidence records and richly connected graphs, with high extraction and relation‑type accuracy, enabling retrieval‑augmented question answering and graph‑based tasks such as link prediction and target prioritization.

By Chang Zong, Jinyu Chen, Sicheng Lv, Si-tu Xue, Huilin Zheng, Jian Wan, Lei Zhang
arXiv Computation and Language
Sep 25

CONSISTRE: A Unified Consistency-Aware Framework for Document-Level Relation Extraction with Large Language Models

CONSISTRE is a consistency‑aware framework for document‑level relation extraction that tackles contradictions in large language model predictions. It offers two tracks: an inference‑time track that refines black‑box LLM outputs through constraint‑aware prompting, verification, and self‑reflection, and a training‑time track that distills consistency knowledge into smaller open‑source models via supervised fine‑tuning and reinforcement learning. Experiments on DocRED show both tracks outperform baselines, with the inference‑time track matching competitive F1 scores and the training‑time track narrowing the performance gap to proprietary LLMs while reducing inference cost.

By Mingxuan Sun
Hugging Face Trending Papers
Jul 27

CONSISTRE: A Unified Consistency-Aware Framework for Document-Level Relation Extraction with Large Language Models

Document-level relation extraction (DocRE) aims to extract relations among multiple entities across extended contexts while maintaining consistency across predicted triples. Although large language models (LLMs) show remarkable reasoning capabilities in information extraction, their predictions are typically generated independently for each candidate triple and may violate fundamental relational constraints such as transitivity, symmetry, and functional uniqueness, leading to contradictory and unreliable outputs.

arXiv AI
Oct 2

LLM-Assisted Discovery of Typed Semantic Links for Ontology Network Construction

The paper presents an automated framework for building ontology networks by discovering typed semantic links between concepts across domains. It uses domain‑adapted DistilBERT embeddings, clustering to prune candidates, and GPT‑4o for generating interpretable relationships, reducing 800k raw pairs to 95k high‑quality candidates. Human validation on 429 links shows an 80.19% precision and 0.890 F1, outperforming five similarity‑based baselines and demonstrating the need for LLM reasoning in ontology link construction.

By Nouha Hayouni, Sheeba Samuel, Alsayed Algergawy
arXiv AI
Oct 7

Aligning LLMs with Biomedical Knowledge using Balanced Fine-Tuning

arXiv:2511.21075v4 Announce Type: replace-cross Abstract: Engineering LLMs to accelerate life sciences research requires a robust alignment with biomedical knowledge. We observe that biomedical text...

By Zhenchao Tang, Fang Wang, Haohuai He, Jiale Zhou, Tianxu Lv, Jun Zhu, Shouzhi Chen, Minghao Yang, Yu Wang, Jiayang Wu, Yidong Song, Yaokun Li, Jiehui Huang, Jun Zhou, Bing He, Jianhua Yao