arXiv AI

Few-Shot Biomedical Relation Extraction with Large Language Models: A Viable Alternative to Supervised Learning?

arXiv:2606. 15412v1 Announce Type: cross Abstract: Biomedical relation extraction (BioRE) is a key step in transforming biomedical literature into structured knowledge.

arXiv Computation and Language
Sep 1

Configurable Semantic Chunking for Biomedical Information Extraction in Retrieval-Augmented Generation

The paper introduces a configurable semantic chunking framework for biomedical information extraction in retrieval‑augmented generation systems. It replaces the fixed‑size chunking stage of BioMedRAG with entity‑preserving windows, trigger‑centered chunking, proposition‑first extraction, tiered trigger prioritization, and hierarchical relation resolution, while keeping the rest of the pipeline unchanged. Experiments on relation extraction benchmarks (GM‑CIHT, DDI, ChemProt) and adverse event classification (ADE) show that the hybrid configuration boosts performance on datasets with explicit relation cues, achieving 82.6% F1 on GM‑CIHT compared to 74.2% with the baseline.

By Riya Ahuja (Institute of Data Science in Biomedicine, TU Braunschweig, Braunschweig, Germany, Braunschweig Integrated Centre of Systems Biology, TU Braunschweig, Braunschweig, Germany), Tim Kacprowski (Institute of Data Science in Biomedicine, TU Braunschweig, Braunschweig, Germany, Braunschweig Integrated Centre of Systems Biology, TU Braunschweig, Braunschweig, Germany), Roya Shiasi Sardoabi (Institute of Data Science in Biomedicine, TU Braunschweig, Braunschweig, Germany, Braunschweig Integrated Centre of Systems Biology, TU Braunschweig, Braunschweig, Germany)
arXiv Computation and Language
Sep 4

PiPMRE: A Pipeline Based on Language Model for Medical Relation Extraction

PiPMRE is a new pipeline for medical relation extraction that uses language models instead of traditional tagging schemes. The framework includes a relation generator that produces multiple relational triplets from a text and a relation filter that scores and selects the most reliable triplets. Experiments on two public datasets show that PiPMRE outperforms previous state‑of‑the‑art methods, improving recall by 5.6 points and accuracy by 4.4 points, and it also performs well in few‑shot scenarios.

By Jiaxin Duan, Fengyu Lu, Junfei Liu
arXiv Computation and Language
Sep 18

Fine-Tuning Models for Biomedical Relation Extraction

The paper introduces pre‑trained models for extracting variant‑phenotype relations from biomedical text, focusing on the SNPPhenA corpus. Fine‑tuning small BERT‑based models, especially DeBERTa, achieves performance close to the current state‑of‑the‑art. Moreover, careful fine‑tuning of Google’s Gemini Pro 1.0 surpasses existing benchmarks on both sentence‑level and abstract‑level relation extraction tasks.

By Claudiu Creanga, Liviu P. Dinu, Daniela Gifu
arXiv Computation and Language
Sep 16

SciNLP: A Domain-Specific Benchmark for Full-Text Scientific Entity and Relation Extraction in NLP

SciNLP is a new benchmark dataset for full‑text entity and relation extraction in the NLP domain, comprising 60 manually annotated papers with 6,429 entities and 1,649 relations. It is the first dataset to provide full‑text annotations of entities and their relationships specifically for NLP literature. Experiments show that models trained on SciNLP outperform baselines on certain tasks, and the dataset enabled the automatic construction of a fine‑grained knowledge graph with an average node degree of 3.3.

By Decheng Duan, Yingyi Zhang, Jitong Peng, Chengzhi Zhang
arXiv AI
Sep 3

BioELX: Context-Aware Cross-lingual Biomedical Entity Linking without Task-Specific Supervision

BioELX is a retrieve‑rerank framework for cross‑lingual biomedical entity linking that tackles two key problems: the English‑biased UMLS alias training data and the degradation caused by naïvely adding context. It fine‑tunes SapBERT_multi with Wikidata‑derived cross‑lingual alias supervision to create shared concept neighborhoods, and then reranks candidates using pretrained LLMs with mention‑anchored prompting to focus on the target mention. Experiments demonstrate state‑of‑the‑art performance on four benchmarks, improving Recall@1 by 4.8–18.2 percentage points without task‑specific annotations.

By Yi Wang, Corina Dima, Liangyu Zhong, Steffen Staab
arXiv AI
Jul 13

TheBioCollection: Unified Pre-Training Scale LLM Corpus for Biology

arXiv:2607. 08803v1 Announce Type: cross Abstract: The push toward large language models for biology (BioLM) has created a need for training corpora that can endow models with a genuine understanding of biology.

By Hyunjin Seo, Hyeon Hwang, Gyubok Lee, Jay Shin, Jimin Park, Taesoo Kim, Sanghoon Lee, Hongjoon Ahn, Sungjun Han, Sangwon Jung
arXiv Computation and Language
Sep 23

BELXTR: Biomedical Entity Linking via Contextualized Token Retrieval

BELXTR is a new biomedical entity linking model that uses a multi‑vector (late interaction) architecture to preserve token‑level matching information, unlike traditional embedding‑based approaches that compress mentions into a single vector. By extending the XTR model with a task‑specific training objective and active query expansion, BELXTR achieves state‑of‑the‑art performance on half of ten evaluated corpora, with an average 5‑percentage‑point gain in recall@1. The model shows especially strong results on cross‑species gene disambiguation, outperforming an LLM‑powered retrieve‑and‑rerank pipeline and approaching a specialized rule‑based system.

By Samuele Garda, Ulf Leser
arXiv AI
Sep 10

Building evidence-based knowledge bases from full-text literature for disease-specific biomedical reasoning

EvidenceNet is a disease‑specific dataset that transforms full‑text biomedical literature into structured evidence records and graph representations, preserving study design, provenance, and quantitative support. Using an LLM‑assisted pipeline, it extracts experimentally grounded findings, normalizes entities, scores evidence quality, and links related records via typed semantic relations. The released subsets—EvidenceNet‑HCC and EvidenceNet‑CRC—contain thousands of evidence records and richly connected graphs, with high extraction and relation‑type accuracy, enabling retrieval‑augmented question answering and graph‑based tasks such as link prediction and target prioritization.

By Chang Zong, Jinyu Chen, Sicheng Lv, Si-tu Xue, Huilin Zheng, Jian Wan, Lei Zhang