arXiv:2608.21497v1 Announce Type: cross
Abstract: Biochemical recurrence (BCR), defined as any detectable prostate-specific antigen level after prostatectomy with confirmatory elevation, is widely us...
By Robert N. Spaans, Catherine Chia, Tongjie Wang, Adam Kowalewski, Parandzem Khachatryan, Domingos Oliveira, Khrystyna Faryna, Jean-Paul A. van Basten, Geert Litjens, Nadieh Khalili
arXiv:2605. 25050v2 Announce Type: replace-cross Abstract: Integrating multimodal datasets in clinical oncology is frequently hindered by high dimensionality and blockwise missingness, where entire data sources are unavailable for specific patient subsets.
By Mohamed Boussena, Florence Monville, Jacques Fieschi-Meric, Frederic Vely, Pierre Milpied, Julien Mazieres, Maurice Perol, Eric Vivier, Laurent Greillier, Fabrice Barlesi, Sebastien Benzekry
arXiv:2608.24688v1 Announce Type: new
Abstract: Precision oncology necessitates a longitudinal model of patient state that captures cancer evolution and treatment over time, integrating multimodal ob...
By Eugene Vorontsov, Yi Kan Wang, Alican Bozkurt, Adam Casson, Ludmila Tydlitatova, Michal Zelechowski, Ezra E. W. Cohen, Jyoti D. Patel, Max Banaszak, Caitlin McWilliams, Shane Colley, Kate Sasser, Ryan Fukushima, Eric Lefkofsky, Razik Yousfi, Siqi Liu
The paper introduces a multimodal dataset for survival prediction in resected pancreatic ductal adenocarcinoma, comprising 302 patients, 446 H&E whole-slide images, clinicopathological variables, targeted sequencing data for 154 patients, and overall survival outcomes. The authors evaluated fourteen survival‑prediction models, finding that a Ridge Cox regression on numeric clinicopathological variables achieved the highest concordance (≈0.65), while multimodal fusion of image and molecular data reached 0.619. These benchmarks provide a foundation for future research and external validation using this pancreas‑specific dataset.
By Anh-Tien Nguyen, Mawuko Tettey, Jacqueline Michelle Metsch, Teresa Zimmer, Niklas Ullrich, Mario Duker, Sandra Rungeling, Kirsten Reuter-Jessen, Tessa Rosenthal, Lena-Christin Conradi, Michael Ghadimi, Alexander Konig, Elisabeth Hessmann, Volker Ellenrieder, Philipp Strobel, Hanibal Bohnenberger, Anne-Christin Hauschild
The paper presents a newly curated, multi-center, multi-modal, and longitudinal lung cancer dataset comprising 1,365 patients with whole-slide images, CT scans, PET scans, structured clinical data, transcriptomics, and follow-up information. The dataset features substantial, non-uniform missingness across modalities, making it ideal for evaluating robust multi-modal fusion strategies. Benchmarks on 12‑month overall survival, disease‑specific survival, and longitudinal hazard prediction demonstrate that integrating complementary modalities consistently outperforms uni-modal approaches, even under severe missing data.
By Rita Cordeiro Mendes, Maria Rita Fonseca Verdelho, Carlos Santiago, Catarina Barata
arXiv:2609.14072v1 Announce Type: new
Abstract: Large Language Models (LLMs) have displayed impressive capabilities in handling tasks that require few demonstration examples, making them effective fe...
By H Mathavan, H Liu