arXiv:2608. 03028v1 Announce Type: new Abstract: Applying a valid medication-safety rule when its patient-specific conditions are not met can produce an incorrect decision.
By Zhitian Hou, Yuhang Liu, Pengkai Wang, Zeyu Liu, Guanghao Zhu, Zheng Liu, Shuo Cai, Congkai Xie, Zhijie Sang, Kun Zeng, Hongxia Yang
FDARxBench is an expert‑curated benchmark designed to evaluate document‑grounded question answering on FDA drug label documents, focusing on generic drug assessment. It features a multi‑stage pipeline that generates high‑quality QA examples covering factual, multi‑hop, and refusal tasks, and includes protocols for both open‑book and closed‑book reasoning. Experiments with various language models show significant gaps in factual grounding, long‑context retrieval, and safe refusal behavior, highlighting the challenge of regulatory‑grade label comprehension.
By Betty Xiong, Jillian Fisher, Benjamin Newman, Meng Hu, Shivangi Gupta, Yejin Choi, Lanyan Fang, Russ B Altman
The paper introduces a framework to predict whether a compound’s potency can be quantified in dose‑response profiling, treating quantifiability as a separate triage goal from biological activity. It shows that features from low‑cost primary screens, rather than molecular structure, strongly predict quantifiability, and that this prediction holds across new chemical scaffolds and assay families. The authors argue that incorporating quantifiability predictions can better allocate expensive dose‑response resources.
By Sean Lim
arXiv:2609.06976v1 Announce Type: new
Abstract: As medical wearables become integrated into daily chronic disease care, effectively interpreting longitudinal monitoring data is essential for patients...
By Yuchen Niu, Yanan Ma, Srinivasan Nandakumar, Maolin Chen, Viktor Schlegel, Kexin Wei, Ling Cheng, Anna Bird, Anil Anthony Bharath, Siew-Kei Lam
arXiv:2610.01938v1 Announce Type: cross
Abstract: Exam-style accuracy does not establish whether large language models (LLMs) reason well over clinical records. We define clinical reasoning as integr...
By Zhangshu Joshua Jiang, Zina Ibrahim, James T. Teo
arXiv:2608. 09080v1 Announce Type: cross Abstract: Large Language Models (LLMs) have achieved strong performance in medical question answering and clinical reasoning tasks.
By Maryam Tahermazandarani, Adnan Mahmood, Fahmida Islam, Quan Z. Sheng