EMR: Self-Evolving Medical Multi-Agent System via Experience Mining and Reuse
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The paper introduces MACD, a Multi-Agent Clinical Diagnosis framework that enables large language models to self‑learn clinical knowledge through a multi‑agent pipeline of summarization, refinement, and application. MACD is extended into a human‑AI collaborative workflow where multiple diagnostician agents consult iteratively, guided by a judge agent and human oversight. Evaluation on the MIMIC‑MACD cohort shows significant gains in diagnostic accuracy—an average 11.6 percentage‑point improvement over authoritative knowledge for open‑weight LLMs and an 18.3‑percentage‑point boost over physician‑only diagnosis in text‑only vignettes.
arXiv:2608. 11420v1 Announce Type: new Abstract: Medical diagnostic reasoning is a high-impact use case for LLMs that carries significant implications for the health and wellbeing of users.
arXiv:2607. 07761v1 Announce Type: new Abstract: Large language models (LLMs) have emerged as important tools in healthcare, showing growing potential for clinical reasoning and patient care.
The paper introduces an ontology‑guided, multi‑agent framework for differential diagnosis that mirrors physicians’ iterative reasoning. By grounding inference in a structured, expert‑curated medical knowledge base, the system produces explicit, auditable reasoning steps, reduces hallucination, and improves transparency. It also identifies key missing symptoms and generates targeted follow‑up questions to lower diagnostic uncertainty.
arXiv:2608.21810v1 Announce Type: cross Abstract: Clinical decision-making is inherently experience-driven: physicians progressively refine their reasoning by synthesizing patient history, multimodal...
arXiv:2610.34878v1 Announce Type: new Abstract: Disease diagnosis is a key application of large language model (LLM) agents in healthcare. However, existing medical agents are primarily trained and e...