arXiv AI

DecNefSimulator: A Modular, Interpretable Framework for Decoded Neurofeedback Simulation Using Generative Models

arXiv:2511. 14555v4 Announce Type: replace-cross Abstract: Decoded Neurofeedback (DecNef) is a promising non-invasive approach to brain modulation with wide-ranging applications in neuromedicine and cognitive neuroscience.

arXiv AI
Sep 24

AI-Driven Neural Surrogates for In Silico Design of Cognitive-Affective Neuromodulation Targets

arXiv:2609.27729v1 Announce Type: cross Abstract: In neuropsychiatry, the primary goal is often not only to decode brain activity but to change it, for example to lessen a negative affective bias or...

By Marco Rothermel, Madleen Stenger, Soroush Daftarian, Svenja Jule Francke, Bita Shariatpanahi, Jos\'e C. Garc\'ia Alanis, Mohammad-Ali Nikouei Mahani, Stefan G. Hofmann, Tim Hahn, Hamidreza Jamalabadi
arXiv AI
2d ago

REALM: Retrospective Encoder Alignment for LFP Modeling

REALM is a retrospective knowledge distillation framework that enables causal decoding of behavior from local field potentials (LFPs). It trains a bidirectional Mamba‑2 teacher on multi‑session data using continuous masked autoencoding, then distills its representations into a compact causal student model. The resulting LFP‑only decoder achieves the highest mean accuracy among compared methods, surpassing state‑of‑the‑art baselines while using fewer parameters and less pretraining time.

By Peicheng Wu, Zhenyu Bu, Runze Ma, Lin Du
arXiv Computation and Language
Sep 3

NS-Copilot: An LLM-Driven Agent System for Autonomous Neuroscience Analysis

NS-Copilot is a large‑language‑model driven multi‑agent system designed to automate neuroscience data analysis. It integrates domain‑specific pre‑trained models for modalities such as EEG and extracellular spike data, and uses a natural‑language interface to orchestrate agents that plan, generate code, and synthesize results. In benchmarks on Alzheimer’s, Parkinson’s, and working‑memory spike decoding, the system consistently outperformed strong baselines across multiple trials.

By Wuche Liu, Yiran Qiao, Linlin Hou, Rui Yang, Shusen Pu, Song Wang, Jing Ma
arXiv Machine Learning
Sep 22

A discrete generative model of neuronal spiking activity on microelectrode arrays

The paper presents a discrete generative model for neuronal spiking activity recorded on microelectrode arrays. It uses a shared vocabulary of spatiotemporal motifs learned by a residual vector‑quantized autoencoder and predicts motif occurrence with a factorized masked transformer. Evaluated on 31 assays from human brain organoids and ex vivo hippocampal tissue, the model achieves superior reconstruction and generation performance compared to baselines and shows that motifs are largely reused across assays.

By Md Sayed Tanveer, Mohammed A. Mostajo-Radji, Ge Wang
arXiv Machine Learning
Sep 7

Brain4FMs: A Benchmark of Foundation Models for Electrical Brain Signal

Brain4FMs is a unified benchmark for evaluating brain foundation models (BFMs) on both scalp EEG and intracranial EEG (iEEG). It incorporates 17 representative models and 21 public datasets spanning clinical diagnosis, sleep staging, communication, and affective computing, and offers dataset-aware preprocessing, cross‑subject evaluation, and standardized downstream workflows. The benchmark highlights that no single BFM consistently outperforms others across all tasks, modalities, and adaptation protocols, prompting further exploratory analyses of model‑specific spatial, spectral, and discrete representations.

By Fanqi Shen, Enhong Yang, Jiahe Li, Junru Hong, Xiaoran Pan, Zhizhang Yuan, Meng Li, Yang Yang