Volumetric medical VQA requires reasoning over long and redundant 3D visual token sequences, especially in multi-sequence MRI where complementary modalities provide diverse diagnostic cues but expose...
arXiv:2604. 09757v2 Announce Type: replace-cross Abstract: Medical vision--language models (VLMs) have shown strong potential for medical visual question answering (VQA), yet their reasoning remains largely text-centric: images are encoded once as static context, and subsequent inference is dominated by language.
By Suyang Xi, Songtao Hu, Yuxiang Lai, Wangyun Dan, Yaqi Liu, Shansong Wang, Xiaofeng Yang
arXiv:2608. 08307v1 Announce Type: cross Abstract: Medical Visual Question Answering (VQA) requires aligning subtle visual evidence, including lesion texture, boundary sharpness, and diffuse density changes, with clinical language.
By Yusra Tariq, Rakesh Chandra Joshi
arXiv:2606. 06534v1 Announce Type: cross Abstract: Longitudinal medical visual question answering (VQA) requires reasoning about anatomical differences between an image of a current time point and an image of a referred time point.
By Jialin Wu, Qianru Zhang, Georges El Fakhri, Xiaofeng Liu
Integrating 3D medical images with vision-language models (VLMs) holds substantial promise for computer-aided diagnosis. However, volumetric images generate prohibitively long visual-token sequences with considerable spatial and inter-slice redundancy.
arXiv:2606. 17412v1 Announce Type: cross Abstract: Pathological images are inherently multi-scale, requiring pathologists to integrate evidence from global tissue architecture at low magnification to cellular morphology at higher magnification for accurate diagnosis.
By Chi Phan, Tianyi Zhang, Qiaochu Xue, Yufeng Wu, Dan Hu, Zeyu Liu, Sudong Wang, Yueming Jin
arXiv:2606. 12169v1 Announce Type: cross Abstract: High-stakes clinical use of large vision-language models (LVLMs) requires reasoning that is grounded in visual evidence and clinical knowledge, not just correct final answers.
By Negin Baghbanzadeh, Pritam Sarkar, Michael Colacci, Abeer Badawi, Adibvafa Fallahpour, Arash Afkanpour, Leonid Sigal, Ali Etemad, Elham Dolatabadi
arXiv:2607. 23794v1 Announce Type: cross Abstract: Pathological diagnosis is inherently multi-scale, requiring the integration of global tissue architecture at low magnification with cellular morphology at higher magnification.
By Chi Phan, Tianyi Zhang, Yufeng Wu, Qiaochu Xue, Jiajie Zhang, Linghan Cai, Zeyu Liu, Sudong Wang, Yueming Jin, Dan Hu
arXiv:2609.24057v1 Announce Type: cross
Abstract: Medical image interpretation is central to diagnosis and care, yet adapting general-purpose multimodal large language models (MLLMs) often requires r...
By Minda Zhao, Fangyu Hu, Yan Luo, Yutong Yang, Jiahui Cai, Kaichen Zhou, Manling Li, Paul Liang, Yilun Du, Lucy Q. Shen, Mengyu Wang
MedProb is a lightweight probing framework that predicts multiple-choice medical visual question answering (Med‑VQA) answers directly from frozen vision‑language model (VLM) representations, avoiding free‑text generation. On datasets such as PATH‑VQA, SLAKE, and VQA‑RAD, MedProb extracts more answer‑relevant signal than prompting and outperforms both medical VLMs and agentic systems. The approach also narrows the performance gap between small and large models, shows that medical adaptation does not consistently improve linear decodability, and reveals positional biases in both prompting and generation.
By Erfan Nourbakhsh, Ke Yang, Anthony Rios
Vision-language pre-training (VLP) holds great promise for general-purpose medical AI by leveraging radiology reports as rich textual supervision, yet existing methods struggle with 3D CT imaging due to inefficient visual backbones and coarse semantic alignment. To address these issues, we propose a tailored VLP framework featuring three key components: (1) a CNN-ViT hybrid encoder that replaces ViT's patch embedding with a 3D CNN backbone to efficiently capture local anatomical details while preserving global attention and compatibility with pre-trained cross-modal priors; (2) a disease-level contrastive learning mechanism using learnable query tokens to dynamically extract disease-specific semantics from full reports and align them with corresponding visual features, thereby disentangling distinct diseases within the same anatomical region; and (3) a diagnosis-aware prompt strategy that employs real clinical phrases and aggregated disease prototypes to bridge the pre-training-inference gap and enhance zero-shot diagnostic reliability.
Pathological diagnosis is inherently multi-scale, requiring the integration of global tissue architecture at low magnification with cellular morphology at higher magnification. However, existing pathology benchmarks and vision-language models (VLMs) are still largely developed under single-scale settings, limiting their ability to learn clinically meaningful multi-magnification reasoning.