arXiv AI

OmniBioTwin: A System-of-Twinned-Systems Framework for Health Digital Twins

arXiv:2606. 11264v1 Announce Type: cross Abstract: Health digital twins (HDTs) promise patient-specific modeling and decision support but current approaches remain structurally fragmented: monolithic models that address a single organ or task lack cross-scale fidelity, while system-level twins lack generalizable architectural frameworks.

Hugging Face Trending Papers
Jun 8

Transition-Based Digital Twin Modelling for Alzheimer's Disease under Sparse Longitudinal Data

Alzheimer's disease (AD) progression is highly heterogeneous and is typically observed through sparse and irregular longitudinal data, posing challenges for prediction and personalised monitoring. Existing machine learning approaches have improved AD prediction using multimodal data, yet often focus on static classification or cohort-level risk estimation, providing limited support for subject-specific modelling and uncertainty-aware reasoning.

arXiv Machine Learning
Jun 25

Neural operator-based digital twins for modeling amyloid-$\beta$ and tau propagation and treatment optimization in Alzheimer's disease

arXiv:2606. 25185v1 Announce Type: new Abstract: Accurately predicting the spatiotemporal evolution of amyloid-$\beta$ and tau proteins at the individual level is critical for improving the diagnosis and treatment of Alzheimer's disease.

By Xiaofeng Xu, Tingting Dan, Zifan Zhou, Bin Li, Guorong Wu, Wenrui Hao
arXiv Machine Learning
Jul 2

Timesynth: A Temporal Fidelity Framework for Health Signal Digital Twins

arXiv:2607. 00431v1 Announce Type: new Abstract: Forecasting models for health-signal digital twins must preserve the oscillatory, frequency, phase, and state-transition dynamics of physiological signals, yet the pointwise metrics used to benchmark them cannot detect when these fundamental properties are lost.

By Md Rakibul Haque, Shireen Elhabian, Warren Woodrich Pettine
arXiv AI
Jun 15

ANSR-DT: A Neuro-Symbolic Framework for Adaptive and Explainable Digital Twins

arXiv:2501. 08561v4 Announce Type: replace Abstract: Digital twins are increasingly used to monitor and optimize industrial systems, yet many existing frameworks remain difficult to interpret, slow to adapt, and limited in their ability to incorporate explicit domain knowledge.

By Safayat Bin Hakim, Muhammad Adil, Alvaro Velasquez, Houbing Herbert Song
arXiv AI
Jul 21

A Continual Validation, Updating, and Decision-Making Framework for Self-Adaptive Digital Twins via Robust Model Predictive Control: A Case Study in Additive Manufacturing

arXiv:2607. 18164v1 Announce Type: cross Abstract: Digital Twins rely on surrogate models to mirror physical systems in real time, yet these models can degrade as operating conditions evolve, a phenomenon known as concept drift.

By Yi-Ping Chen, Ying-Kuan Tsai, Vispi Karkaria, Seul Lee, Daniel Apley, Wei Chen