arXiv:2608. 02135v1 Announce Type: cross Abstract: Cardiovascular digital twins aim to create patient-specific computational models that evolve with clinical data to support diagnosis, prognosis, and therapy optimisation.
By Emmanuel Lwele, Francis Chikweto
arXiv:2606. 27334v1 Announce Type: new Abstract: Digital twins have emerged as a promising paradigm for personalized healthcare, enabling modeling of individual behavior and health trajectories.
By Mohammad Mehdi Hosseini, Mohammad H. Mahoor, Hiroko H. Dodge
arXiv:2608. 14969v1 Announce Type: new Abstract: We present a physiology-informed digital twin of the human liver designed for longitudinal simulation of liver function and early-stage disease progression.
By Sumaiya Afroz Mila, Sandip Ray
Alzheimer's disease (AD) progression is highly heterogeneous and is typically observed through sparse and irregular longitudinal data, posing challenges for prediction and personalised monitoring. Existing machine learning approaches have improved AD prediction using multimodal data, yet often focus on static classification or cohort-level risk estimation, providing limited support for subject-specific modelling and uncertainty-aware reasoning.
arXiv:2606. 25185v1 Announce Type: new Abstract: Accurately predicting the spatiotemporal evolution of amyloid-$\beta$ and tau proteins at the individual level is critical for improving the diagnosis and treatment of Alzheimer's disease.
By Xiaofeng Xu, Tingting Dan, Zifan Zhou, Bin Li, Guorong Wu, Wenrui Hao
arXiv:2606. 09671v1 Announce Type: cross Abstract: Alzheimer's disease (AD) progression is highly heterogeneous and is typically observed through sparse and irregular longitudinal data, posing challenges for prediction and personalised monitoring.
By Yinyu Huang, Yilin Zhang, Sofia Michopoulou, Christopher Kipps, Rahman Attar
arXiv:2606. 18154v1 Announce Type: new Abstract: Building personalized cardiac electrophysiology (EP) digital twins requires identifying the appropriate model structure for each patient, not merely fitting parameters.
By Ziqi Zhou, Yubo Ye, Sumeet Atul Vadhavka, Linwei Wang, Zhiqiang Tao
arXiv:2607. 00431v1 Announce Type: new Abstract: Forecasting models for health-signal digital twins must preserve the oscillatory, frequency, phase, and state-transition dynamics of physiological signals, yet the pointwise metrics used to benchmark them cannot detect when these fundamental properties are lost.
By Md Rakibul Haque, Shireen Elhabian, Warren Woodrich Pettine
arXiv:2607. 03585v1 Announce Type: new Abstract: Engineering Digital Twins and Prognostics and Health Management (PHM) systems rely on robust perception modules to extract actionable information from heterogeneous and non-stationary time-series data.
By Quang Hung Pham, Ryad Zemouri, Martin Gagnon, Luc Vouligny
arXiv:2501. 08561v4 Announce Type: replace Abstract: Digital twins are increasingly used to monitor and optimize industrial systems, yet many existing frameworks remain difficult to interpret, slow to adapt, and limited in their ability to incorporate explicit domain knowledge.
By Safayat Bin Hakim, Muhammad Adil, Alvaro Velasquez, Houbing Herbert Song
arXiv:2607. 08793v1 Announce Type: cross Abstract: Sepsis is a leading cause of mortality, yet optimal treatment policies remain contested.
By Joshua Pickard, Wei Qi, Na Li, Ann Woolley, Lisa Cosimi, Roy Kishony, Deborah Hung
arXiv:2607. 18164v1 Announce Type: cross Abstract: Digital Twins rely on surrogate models to mirror physical systems in real time, yet these models can degrade as operating conditions evolve, a phenomenon known as concept drift.
By Yi-Ping Chen, Ying-Kuan Tsai, Vispi Karkaria, Seul Lee, Daniel Apley, Wei Chen