arXiv Computation and Language

LLM-Anchored Paralinguistic Enrichment for Alzheimer's Disease Detection

The paper introduces LLM-Anchored Paralinguistic Enrichment (LAPE), a method that enhances language model representations with speech-based paralinguistic cues such as pauses and word elongations. LAPE incorporates three innovations: prosodic event textualization, lexico-prosodic unitization and chunking, and text-anchored paralinguistic fusion using NormGate. Evaluations on the ADReSS and ADReSSo datasets show that LAPE achieves state‑of‑the‑art performance in detecting Alzheimer’s disease from speech.

arXiv Computation and Language

Sep 28

Why Alzheimer's Speech Screening Fails to Generalize: Bridging the Deployment Gap via Cross-Corpus Evidence Anchoring

The paper examines why speech‑based screening for Alzheimer’s disease fails to generalize across different languages, tasks, and recording protocols. Using a leave‑one‑corpus‑out evaluation on four datasets, it finds that 59 of 70 interpretable speech features show conflicting patterns between healthy controls and cognitive risk groups, with pause, silence, and speech rate being highly protocol‑sensitive. The authors propose a fusion method that combines XLM‑R text baseline scores with evidence anchors, improving mean speaker AUC to 0.785 and worst‑case AUC to 0.615, and emphasize the importance of auditing feature transferability and reporting worst‑case domain robustness.

By Zijian Lu, Sizhe Liu, Yin Zhang, Jixuan Deng, Xinrong Lin, Xinchen Yuan, Chicheng Jin, Yiping Zuo, Yuanchao Li

arXiv AI

Jul 1

Listening Between the Lines: Joint Learning of ASR Embeddings and LLM-Augmented Linguistics for Dementia Detection

arXiv:2606. 30675v1 Announce Type: cross Abstract: Early detection of dementia through speech analysis offers a non-invasive screening alternative, but capturing both acoustic and linguistic biomarkers remains challenging.

By Olivier Jiyoun Jung, Jonghyeon Park, Myungwoo Oh

llms rag multimodal benchmarks

arXiv AI

Jul 14

Transcript-Free Lightweight Detection of Alzheimer's Disease from Spontaneous Speech Using Handcrafted MFCC-Dominant Acoustic Biomarkers

arXiv:2607. 10168v1 Announce Type: cross Abstract: It is still hard to find Alzheimer's disease (AD) early, especially when neuroimaging is expensive or tools that depend on language are not available.

By Rashin Gholijani Farahani, Azam Bastanfard

multimodal

arXiv Machine Learning

Oct 12

Acoustic Biomarkers for Alzheimer's Disease Detection from Spontaneous Speech

The study explores acoustic biomarkers derived from spontaneous speech to differentiate Alzheimer's disease patients from healthy controls. Using a structured picture‑description task, low‑level prosodic, spectral, and temporal features were extracted and fed into various machine learning classifiers. The best models achieved clinically meaningful separation between diagnostic groups, indicating that non‑invasive audio screening could aid early detection of dementia.

By Anh L Tran, Arjee Javellana Restar, Bereket Kindo

multimodal

arXiv AI

Jun 2

What Do LLMs Know About Alzheimer's Disease? Multi-loss Fine-Tuning and Probing for AD Detection

arXiv:2602. 11177v2 Announce Type: replace-cross Abstract: Reliable early detection of Alzheimer's disease (AD) is challenging, particularly due to the limited availability of labeled data.

By Lei Jiang, Yue Zhou, Natalie Parde

llms fine-tuning benchmarks

arXiv AI

Jul 1

ASR-Agnostic Multimodal Spectrotemporal Modeling for Early Dementia Detection

arXiv:2606. 30646v1 Announce Type: cross Abstract: Speech recruits the same executive, attentional, and working memory processes underlying instrumental activities of daily living, or IADLs, providing a non-invasive proxy for cognitive assessment.

By Chukwuemeka Ugwu, Oluwafemi Richard Oyeleke

llms rag multimodal benchmarks

Hugging Face Trending Papers

Jun 4

Multilingual Detection of Alzheimer's Disease from Speech: A Cross-Linguistic Transfer Learning Approach

The development of multilingual Alzheimer's Disease Dementia (AD) detection models presents significant challenges due to the resource-intensive and time-consuming nature of language-specific model training. We propose a novel solution using cross-language training to detect AD in languages beyond those used for model training.

llms fine-tuning

arXiv AI

Jun 30

LoRA-Tuned Large Language Models for Dementia Detection via Multi-View Speech-Derived Features

arXiv:2606. 28445v1 Announce Type: cross Abstract: Early detection of dementia enables timely intervention, and reflecting cognitive impairment, spontaneous speech offers a non-invasive screening modality.

By Jonghyeon Park, Olivier Jiyoun Jung, Myungwoo Oh

llms fine-tuning multimodal benchmarks

arXiv Machine Learning

Jul 24

Toward Generalizable Cognitive Impairment Detection with Speech-Based Multimodal Large Language Models

arXiv:2607. 21496v1 Announce Type: cross Abstract: Cognitive impairment (CI) is a growing public health concern.

By Yingchao Huang, Xin Wang, Yuhan Su, Shanshan Yao

llms rag multimodal benchmarks safety

arXiv AI

Sep 2

Cleaner Speech, Weaker Generalization: Revisiting Pitt-Derived Benchmarks for Alzheimer's Disease Detection

The study examines how speech preprocessing—such as enhancement, sample selection, and demographic balancing—affects Alzheimer’s disease detection models that use the Pitt Corpus. Experiments reveal that while speech‑enhanced datasets boost in‑domain accuracy, they diminish cross‑dataset robustness and introduce class imbalance and prediction shifts, even when training and testing enhancements are matched. Large audio‑language models show similar sensitivity, indicating that cleaner speech does not guarantee better real‑world performance.

By Luqi Sun, Shreeram Suresh Chandra, Lin Zhang, You-Jin Li, Brian MacWhinney, Yu Tsao, Emily Mower Provost, Berrak Sisman

llms benchmarks

arXiv Machine Learning

Sep 15

CCMAN: Cognitive Instability-Aware Cross-Modal Attention Network for Interpretable Temporal Biomarkers of Verbal Fluency Speech

arXiv:2609.14764v1 Announce Type: cross Abstract: Early detection of cognitive decline from speech offers a scalable and non-invasive alternative to conventional clinical assessment. Verbal fluency t...

By Madhurananda Pahar, Caitlin Illingworth, Dorota Braun, Daniel Blackburn, Heidi Christensen

llms fine-tuning multimodal benchmarks

arXiv Machine Learning

Jul 28

Dementia classification from spontaneous speech using wrapper-based feature selection

arXiv:2502. 03484v3 Announce Type: replace-cross Abstract: Dementia encompasses a group of syndromes that impair cognitive functions such as memory, reasoning, and the ability to perform daily activities.

By Marko Niemel\"a, Mikaela von Bonsdorff, Sami \"Ayr\"am\"o, Tommi K\"arkk\"ainen

Related stories