The paper introduces a new method for timely risk classification in clinical monitoring, framing the problem as a multi‑objective optimization that balances early classification, sensitivity, specificity, and monitoring cost. It derives an optimal decision rule via a value recursion and estimates it from data using a recurrent neural network combined with a primal–dual updating scheme to enforce performance constraints. Experiments, including a case study on continuous glucose monitoring for hypoglycemia prediction, show that the approach produces accurate, timely decision rules that meet the specified operating characteristics.
arXiv:2608. 15309v1 Announce Type: new Abstract: Continuous multimodal sensing now allows human physiology to be observed throughout daily life rather than only during occasional clinical visits.
arXiv:2605. 31014v2 Announce Type: replace Abstract: Multi-omics data provide complementary molecular characterizations of disease phenotypes and play an important role in disease diagnosis and subtype classification in precision medicine.
arXiv:2606. 01028v1 Announce Type: new Abstract: Medical treatment recommendation poses several challenges to reinforcement learning (RL): patient physiology evolves in continuous time, measurements and interventions are performed at irregular intervals, and treatment effects vary substantially across individuals.
arXiv:2604. 23954v2 Announce Type: replace Abstract: Artificial Intelligence (AI) and Machine Learning (ML) models used in clinical settings are increasingly deployed to support clinical decision-making.
arXiv:2608. 10969v1 Announce Type: new Abstract: Healthcare data, such as Intensive Care Unit (ICU) records, comprise heterogeneous multivariate time series sampled at irregular intervals with pervasive missingness.
arXiv:2606. 16337v1 Announce Type: new Abstract: Predictive modeling for clinical tabular data is central to clinical decision support and therefore requires not only strong predictive performance but also transparent decision logic.
arXiv:2608.29419v1 Announce Type: cross Abstract: Deep learning architectures are increasingly proposed for patient trajectory modeling in electronic health records (EHRs), yet their advantage over s...
arXiv:2602. 00541v2 Announce Type: replace Abstract: Clinical events captured in Electronic Health Records (EHR) are irregularly sampled and may consist of a mixture of discrete events and numerical measurements, such as laboratory values or treatment dosages.
arXiv:2606. 27694v1 Announce Type: cross Abstract: Randomized Smoothing (RS) provides rigorous robustness guarantees for neural networks without architectural constraints, yet its adoption is limited by extreme computational costs.
arXiv:2505. 04757v2 Announce Type: replace Abstract: This paper introduces a novel approach to contextual stochastic optimization, integrating operations research and machine learning to address decision-making under uncertainty.
arXiv:2605. 27991v2 Announce Type: replace-cross Abstract: Gradient-flow optimization is usually viewed as an algorithmic procedure for minimizing empirical loss, with training duration selected by validation or heuristic early-stopping rules.
arXiv:2606. 01051v1 Announce Type: new Abstract: Dynamic medical treatment requires deciding treatment intensity and intervention timing, while patient states evolve continuously and adverse events may occur between clinical interactions.