arXiv AI

PsyCIDRA: A Dual-Agent Framework for Psychiatric Interviewing and Diagnostic Reasoning

PsyCIDRA is a dual‑agent framework that couples a free‑form psychiatric interviewer with a diagnostic reasoning agent to support expert review. The interviewer agent uses tools to keep working notes, load expert skills, and pull ICD‑11 references, while the diagnostic agent receives the interview transcript and generates hypotheses with supporting, conflicting, and missing evidence, withholding a final hypothesis if insufficient support exists. In simulations and a blinded human study, PsyCIDRA achieved higher diagnostic agreement and rank‑1 accuracy than direct prompting, indicating its promise for assisting psychiatric assessment through interactive dialogue.

arXiv AI
Jul 10

MentalHospital: A Virtual Environment for Evaluating Psychiatric Clinical Encounters

arXiv:2607. 08257v1 Announce Type: new Abstract: Large language models (LLMs) have shown strong performance on isolated psychiatric tasks, including dialogue, diagnosis, and treatment planning, yet existing benchmarks rarely simulate complete psychiatric clinical encounters.

By Yuming Yang, Xiao Sun, Yuanwei Zou, Zhengxiao Wu, Yun Chen, Jiang Zhong, Haoyang Zeng, Jingwang Huang, Kaiwen Wei
arXiv AI
Sep 12

Evaluating Scaffolding-Oriented Multi-Agent Large Language Model System for Clinical Interview Training

The study introduces a scaffolding-oriented multi-agent Large Language Model (LLM) AI Standardized Patient (AI-SP) platform designed to train medical students in patient interviews. In a randomized controlled trial with 100 students, the multi-agent system—comprising a patient agent, a Socratic tutor agent, and a turn-level evaluator—did not improve diagnostic accuracy but significantly enhanced overall OSCE scores, especially in communication, empathy, and history-taking. The authors also release a richly annotated dataset to support further research in AI-supported clinical reasoning training.

By Luming Yang, Haoxian Liu, Siqing Li, Rong Jia, Yue Xiao, Guanhua Chen, Li Lu
arXiv Computation and Language
Sep 1

Evidence-Bounded Mental Health Reasoning from Heterogeneous Speech Protocols

The paper introduces Evidence-Bounded Mental Health Reasoning, addressing the problem that current multimodal mental health screening models treat all clinical speech protocols as equally evidential. It presents the Evidence Package Benchmark, comprising 1,870 annotated packages from six diverse protocols, and proposes EviBound, a protocol-aware framework that limits reasoning to valid evidence using a planner, acoustic consensus, and a boundary critic. EviBound outperforms existing omni-modal baselines, achieving a Depression AUROC of 0.8658 with no claim violations.

By Chengyuan Gao, Jiang Wu, Tao Lu, Jiayan Guo, Mingkun Xu, Tianyi Zang, Shangyang Li
arXiv AI
Sep 21

Clinician-Grounded Quality Assurance for AI-Assisted Psychiatric Intake

The paper introduces a clinician‑grounded evaluation platform called InterviewPlayground, which uses a memory‑augmented patient simulator to assess AI‑assisted psychiatric intake systems. It supports comparison across different interviewing styles, reduces clinician workload, and measures clinically relevant performance. In a pilot study, a GPT‑based intake interviewer captured more relevant items but made more unfounded inferences and missed safety concerns compared to clinicians.

By King Shi, Amanda Li, Jonathan Ivey, Synthia Qia Wang, Guan Gui, Hyunseo Kim, Peter Zandi, Jason Straub, Jacob Taylor, Ananya Joshi
arXiv AI
Jul 16

Ask Before You Diagnose: Safe-Psych, a Sequential Evaluation Benchmark for LLMs in Psychiatry

arXiv:2607. 13036v1 Announce Type: cross Abstract: Large language models (LLMs) are increasingly used for decision support in healthcare, but clinical evidence is often incomplete or evolving.

By Oriana Presacan, Andreea Grama, Larisa Irimin\u{a}, Alireza Nik, Jaya Ojha, Vajira Thambawita, Ciprian I. B\u{a}cil\u{a}, Bogdan Ionescu, Michael A. Riegler
arXiv AI
Aug 14

MARC v1: An Open-Source Multi-Agent Framework for Clinical AI Reasoning and Coordination

arXiv:2608. 13476v1 Announce Type: new Abstract: We present Multi-Agent Reasoning and Coordination (MARC), an open-source framework that replaces monolithic LLM prompting with deterministic multi-agent orchestration for clinical reasoning.

By Saisha Shetty, Satvik Tripathi, Austin Lin, Colin Zhao, Theodore Kim, Don Enwerem, Jacinta Arnold, Shahriar Faghani, Tessa S Cook