arXiv AI

Clin-JEPA: A Multi-Phase Co-Training Framework for Joint-Embedding Predictive Pretraining on EHR Patient Trajectories

arXiv:2605. 10840v3 Announce Type: replace-cross Abstract: We present Clin-JEPA, a multi-phase co-training framework for joint-embedding predictive (JEPA) pretraining on EHR patient trajectories.

arXiv Machine Learning
Jul 30

CalTwin: Towards Calibrated, Shift-Robust Medical World Models via Fisher-Information Regularisation

arXiv:2607. 26752v1 Announce Type: new Abstract: Medical world models aim to learn a latent state of patient or organ physiology and a transition function that forecasts how that state evolves under interventions, supporting downstream tasks from imaging-based diagnosis to digital-twin treatment planning.

By Behraj Khan, Shabir Ahmad, Syed Ahmad Chan Bukhari, Tahir Qasim Syed
arXiv AI
Jun 8

LuMamba: Latent Unified Mamba for Electrode Topology-Invariant and Efficient EEG Modeling

arXiv:2603. 19100v2 Announce Type: replace Abstract: Electroencephalography (EEG) enables non-invasive monitoring of brain activity across clinical and neurotechnology applications, yet building foundation models for EEG remains challenging due to differing electrode topologies and computational scalability, as Transformer architectures incur quadratic sequence complexity.

By Dana\'e Broustail, Anna Tegon, Thorir Mar Ingolfsson, Yawei Li, Luca Benini
arXiv AI
Sep 15

Freezing the Physiological Encoder: Explanation Stability Under Bounded Updates of an ICU Model

The paper introduces a bounded updating framework for ICU prediction models that freezes the physiological encoder while allowing updates only to the treatment pathway and fusion head. Experiments on 84,792 MIMIC-IV ICU stays across four temporal shifts show that selective adaptation yields more stable explanations—higher rank correlation, better top‑5 feature agreement, and improved retrieval stability—compared to full model adaptation. Predictive performance varies by outcome, but the results demonstrate that explanation stability is governed by the structural boundaries of allowed adaptation rather than merely by freezing components.

By Fatema Ferdous Tamanna, K. M. Merajul Arefin, Md. Abdul Masud
arXiv Machine Learning
Jul 27

Autoregressive EHR Foundation Models with Multimodal Inputs

arXiv:2607. 22264v1 Announce Type: new Abstract: Autoregressive foundation models trained on tokenized electronic health records (EHRs) can support zero-shot clinical prediction, yet most operate on structured event codes alone, and do not incorporate multiple modalities in a principled way.

By Yuxuan Liu, Joshua Placidi, Jinpei Han, Alfred John Balston, Marek Rei, A. Aldo Faisal
arXiv Computation and Language
Sep 18

JEPA-Anything: Learning Predictive Models across Different Worlds

JEPA-Anything is a domain‑agnostic framework that uses orthogonal predictive factorization (OPF) to decompose latent targets into complementary factors, learn them via dedicated pathways, and recombine them for shared prediction. The method is evaluated across seven diverse domains—vision, biology, clinical trajectories, control, molecular dynamics, physical fields, and weather—showing improvements on 10 dynamics tasks, reduced error on Interventional Pong, and lowest one‑step and 100‑step molecular errors among compared methods. Experimental validation includes a factor‑nominated biological intervention that succeeded in cell co‑cultures, organoids, tumor fragments, and mice, and latent orbital modes that recover the Keplerian scaling exponent.

By Taoyong Cui, Zhongyao Wang, Xinyue Xu, Weiyang Liu, Zhaochen Yu, Yuying Zhang, Qiang Gao, Mengyue Yang, Wanli Ouyang, Pheng Ann Heng, Yingcheng Wu, Zhenfei Yin, Ling Yang
Hugging Face Trending Papers
Aug 20

Orthogonal JEPA: Factorized Predictive States for Latent World Models

Orthogonal JEPA introduces a latent world‑modeling framework that factorizes predictive states into orthogonal components. By learning basis matrices and dedicated prediction branches, the method reduces redundancy and improves gradient signals for less dominant predictive structures. The factorized states can be synthesized into complete latent representations for downstream tasks such as decoding, planning, or autoregressive rollout, and are evaluated across vision, biology, health, control, and molecular dynamics domains.

arXiv Machine Learning
Jul 2

LeNEPA: No-Augmentation Next-Latent Prediction for Time-Series Representation Learning

arXiv:2607. 00958v1 Announce Type: new Abstract: Time series are central to modern data mining applications, from industrial telemetry and server metrics to finance and physiology, yet time-series self-supervised learning often depends on view and augmentation choices that encode domain-specific invariances.

By Alexander Chemeris, Ming Jin, Randall Balestriero