arXiv Machine Learning

Connectome-to-Function: Conditional Generative Latent Representations for Reservoir Computing

arXiv Machine Learning
Jul 23

Geometry-Guided Generative Representation for Functional Brain Graphs

arXiv:2511. 04539v2 Announce Type: replace-cross Abstract: In network neuroscience, functional brain systems are often characterized using separate yet related graph-theoretic or spectral descriptors, overlooking how these properties covary and partially overlap across individuals and conditions.

By Subati Abulikemu, Tiago Azevedo, Michail Mamalakis, John Suckling
arXiv Machine Learning
Oct 9

BrainATCL: Adaptive Temporal Brain Connectivity Learning for Functional Link Prediction and Age Estimation

BrainATCL is an unsupervised, nonparametric framework that learns adaptive temporal brain connectivity from resting‑state fMRI data. It dynamically adjusts the lookback window for each snapshot based on newly added edges and encodes graph sequences with a GINE‑Mamba2 backbone, incorporating brain‑structure and function‑informed edge attributes. The method is evaluated on functional link prediction and age estimation, showing superior performance and strong generalization, even across sessions.

By Yiran Huang, Amirhossein Nouranizadeh, Christine Ahrends, Mengjia Xu
arXiv AI
Jul 9

Latent graph encoding of multimodal neuroimaging features with generative AI architectures

arXiv:2607. 07027v1 Announce Type: cross Abstract: While generative models enable encoding of complex neuroimaging data for feature generation and reconstruction, developing optimal architectural frameworks with appropriate encoding and latent space processes is crucial for studying structural and functional properties of the brain.

By Ishaan Batta, Meenu Ajith, Vince Calhoun
arXiv Machine Learning
Sep 7

Reservoir-Based Graph Convolutional Networks

The paper introduces RGC‑Net, a Reservoir‑Based Graph Convolutional Network that combines fixed‑random reservoir dynamics with a structured convolutional framework for graph learning. It addresses limitations of existing reservoir‑based GNNs by adding a leaky integrator for better feature retention and a robust, adaptable architecture for graph classification and generation. Experiments demonstrate state‑of‑the‑art performance on classification and generative tasks, including dynamic brain connectivity, with faster convergence and reduced over‑smoothing.

By Mayssa Soussia, Gita Ayu Salsabila, Mohamed Ali Mahjoub, Islem Rekik
arXiv Machine Learning
Oct 5

Structural-Functional Brain Connectivity Generation via Multimodal Hypergraph-based Flow Matching

The paper introduces Multimodal Hypergraph Flow Matching (MHG‑FM), a framework that jointly generates structural connectivity (SC) and functional connectivity (FC) by constructing modality‑specific hypergraphs and learning higher‑order representations with Hypergraph Neural Network encoders. It employs Dual Cross‑Attention for bidirectional cross‑modal fusion, a variational autoencoder to map fused representations into a latent space, and conditional flow matching to synthesize connectivity and perform multimodal translation. Experiments on the Human Connectome Project Young Adult dataset demonstrate that MHG‑FM outperforms state‑of‑the‑art baselines in reconstruction quality, topology preservation, distributional similarity, and SC‑FC coupling, while achieving roughly eight times faster sampling than a comparable diffusion backbone.

By Chyong Yi Poh, Hwa Hui Tew, Junn Yong Loo, Rapha\"{e}l C. -W. Phan, Fuad Noman, Pew-Thian Yap, Chee-Ming Ting
arXiv Machine Learning
Sep 29

Supervised Deep Multimodal Matrix Factorization for Interpretable Brain Network Analysis

The paper introduces Supervised Deep Multimodal Matrix Factorization (SD3MF), an interpretable framework that extends Symmetric Nonnegative Matrix Tri-Factorization to supervised prediction across populations of multimodal brain graphs. SD3MF learns deep hierarchical factorizations for each modality and a shared latent representation, jointly optimizing graph reconstruction and prediction while enabling data-driven multimodal fusion. Experiments on multimodal connectome datasets demonstrate that SD3MF outperforms strong deep learning baselines such as CNNs and GNNs, providing biologically interpretable insights through community-level interaction matrices.

By Amjad Seyedi, Lifang He, Songlin Zhao, Akwum Onwunta, Nicolas Gillis
arXiv AI
Sep 30

BrainNet Studio: A Unified Toolkit for Brain Network Construction, Intelligent Analysis, and Visualization

BrainNet Studio is a unified toolkit that enables the construction, analysis, and visualization of both static and dynamic brain networks. It integrates 27 algorithms—including deep learning, graph neural networks, and spatiotemporal sequence models—to support classification, biomarker identification, and the extraction of discriminative brain regions and connections. The toolkit also employs a large language model to generate researcher‑verifiable summaries of functional and structural connectivity, as well as structure‑function coupling, at individual and group levels.

By Xiwei Zeng, Shengrong Li, Yiheng Liu, Chunwei Tian, Daoqiang Zhang, Qi Zhu
arXiv Machine Learning
Oct 5

A Generative Model of Complex Networks Using Graphons and Neural Inverse Operators

The paper introduces a generative graph model that combines mechanistic interpretability with amortized inference by formulating both the generative process and parameter recovery in function space. It extends step graphons to a multifractal construction, enabling a neural inverse operator that can infer parameters for unseen graph sizes. Experiments show the model outperforms a pretrained graph foundation model on zero‑shot generation and matches instance‑specific methods on single‑observation networks, while also sensitively tracking brain state changes in an EEG study.

By Wooseong Choi, Italo'Ivo Lima Dias Pinto, Chen Sun, Gaurav Gupta, Dong Song, Paul Bogdan