arXiv AI

iLENS: Interpretable LLM-Guided Mixture-of-Experts for Neuroimaging Survival Analysis

arXiv:2607. 08778v1 Announce Type: cross Abstract: Alzheimer's Disease (AD) is a complex neurodegenerative disorder that continues to impact millions of people worldwide.

Hugging Face Trending Papers
Jun 23

Uncertainty-Aware Longitudinal Forecasting of Alzheimer's Disease Progression Using Deep Learning

Longitudinal modelling of Alzheimer's disease progression is clinically useful only if it can describe not just the most likely next diagnosis, but how a patient may evolve over time and how reliable that forecast is. Most deep learning approaches reduce this problem to single-step classification, treating cognitively normal, mild cognitive impairment, and dementia as flat categories while providing limited insight into how uncertainty accumulates across future visits.

arXiv AI
Jun 2

A Monosemantic Attribution Framework for Stable Interpretability in Clinical Neuroscience Transformer-Based Language Models

arXiv:2601. 17952v2 Announce Type: replace-cross Abstract: Interpretability remains a key challenge for deploying language models (LM) in clinical settings such as progression diagnosis of Alzheimer disease, where early and trustworthy predictions are essential.

By Michail Mamalakis, Tiago Azevedo, Cristian Cosentino, Chiara D'Ercoli, Subati Abulikemu, Zhongtian Sun, Richard Bethlehem, Pietro Lio
Hugging Face Trending Papers
Jun 8

From Hazard Functions to Language Space: Cox-Supervised Distillation of Survival Risk into a Large Language Model

We investigate whether information about time-to-event risk estimated by a Cox proportional hazards model can be transferred into a generative large language model. We propose a text-based survival modelling pipeline in which structured clinical covariates are converted into text prompts and a Qwen-based large language model is fine-tuned to generate patient-specific survival risk using Cox model predictions as a training target.

arXiv Machine Learning
Jul 14

Imputation-free transformer learning enables robust Alzheimer's disease prediction and calibrated uncertainty quantification across heterogeneous clinical cohorts

arXiv:2607. 11656v1 Announce Type: cross Abstract: Accurate diagnostic classification and disease-severity prediction for Alzheimer's disease are hampered by the incompleteness and heterogeneity of real-world clinical data.

By Christelle Schneuwly Diaz, Narmina Baghirova, Duy-Thanh Vu, Duy-Cat Can, Gilles Allali, Philippe Ryvlin, Oliver Y. Ch\'en