arXiv:2606. 05139v1 Announce Type: new Abstract: The rapid advancement of high-throughput sequencing has led to large, high-dimensional omics datasets.
arXiv:2605. 18629v2 Announce Type: replace Abstract: Sparse autoencoders (SAEs) are one of the main methods to interpret the inner workings of deep neural networks (DNNs), decomposing activations into higher-dimensional features.
arXiv:2608.07632v2 Announce Type: replace-cross Abstract: Image-based profiling captures rich phenotypic signatures for drug discovery and functional genomics. Large public datasets like JUMP Cell Pa...
MODIS is a semi‑supervised framework for integrating multi‑omics data that are often unpaired, partially labeled, and scarce, such as in rare disease studies. It trains on a large reference database and a small target dataset simultaneously, using diagonal integration and class‑label alignment to handle class imbalance. The architecture combines variational auto‑encoders, a class classifier, and an adversarially trained modality classifier, with a regularized relativistic GAN loss for stable training, and demonstrates high accuracy on synthetic data and the TCGA cancer dataset.
arXiv:2512. 17678v2 Announce Type: replace-cross Abstract: Selecting compact and informative gene subsets from single-cell transcriptomic data is essential for biomarker discovery, improving interpretability, and cost-effective profiling.
arXiv:2608. 06993v1 Announce Type: cross Abstract: Large-scale pretrained time-series models achieve strong results through large-scale pretraining and task-agnostic representation learning, but they rely on abundant, diverse data that industrial and scientific domains often lack.
arXiv:2608. 08182v1 Announce Type: cross Abstract: Machine learning models for MALDI-TOF mass spectrometry have shown considerable promise for clinical microbiology tasks such as microbial identification and antimicrobial resistance prediction.
CellMSA introduces a novel single‑cell representation learning framework that leverages a multiple‑sequence‑alignment‑inspired context model. For each target cell, it retrieves relevant cells across batches and related cell types, summarizing cross‑cell patterns into a context‑dependent gene‑pair representation that is fed into a pair‑aware encoder. Pretraining on a massive human single‑cell corpus (≈109 million cells) and subsequent benchmarks demonstrate consistent performance gains over existing methods.
arXiv:2608. 06727v1 Announce Type: new Abstract: Transformer models for high-dimensional omics analysis process thousands of genes or pathways, although only a subset requires deep computation.
arXiv:2602. 17330v5 Announce Type: replace-cross Abstract: Comparative analysis of adaptive immune repertoires at population scale is hampered by two practical bottlenecks: the near-quadratic cost of pairwise affinity evaluations and dataset imbalances that obscure clinically important minority clonotypes.
arXiv:2608.28923v1 Announce Type: cross Abstract: Data augmentation is a cornerstone of deep learning pipelines, yet existing strategies treat it as a static, model-agnostic preprocessing step, eithe...
arXiv:2603. 13377v2 Announce Type: replace-cross Abstract: Representation learning has driven major advances in natural image analysis by enabling models to acquire high-level semantic features.
arXiv:2608. 02690v1 Announce Type: new Abstract: On-device training of deep neural networks is fundamentally constrained by the computational and memory costs of large-scale datasets.