The paper introduces an unsupervised machine learning framework that fuses heterogeneous genomic and clinical data using tensor decomposition and clustering to predict cancer risk levels. By extracting latent, biologically meaningful features through tensor decomposition, the approach outperforms unimodal feature sets. Experiments on LinkedOmics data of 11,158 patients across 32 cancer types show that the tSVD+GMM configuration consistently achieves superior performance on clinical benchmarks such as tumor purity, pathological stage, and survival outcomes.
arXiv:2610.07694v1 Announce Type: new Abstract: The integrative analysis of histopathological Whole-Slide Images (WSIs) and transcriptomic profiles holds significant promise for cancer survival predi...
arXiv:2510.06113v2 Announce Type: replace Abstract: Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which red...
The paper presents a newly curated, multi-center, multi-modal, and longitudinal lung cancer dataset comprising 1,365 patients with whole-slide images, CT scans, PET scans, structured clinical data, transcriptomics, and follow-up information. The dataset features substantial, non-uniform missingness across modalities, making it ideal for evaluating robust multi-modal fusion strategies. Benchmarks on 12‑month overall survival, disease‑specific survival, and longitudinal hazard prediction demonstrate that integrating complementary modalities consistently outperforms uni-modal approaches, even under severe missing data.
arXiv:2606. 17115v1 Announce Type: cross Abstract: Foundation models (FMs) have emerged as powerful representation extractors for medical data, yet their generalizability to datasets under distribution shift remains underexplored.
arXiv:2609.14072v1 Announce Type: new Abstract: Large Language Models (LLMs) have displayed impressive capabilities in handling tasks that require few demonstration examples, making them effective fe...
arXiv:2608. 02769v1 Announce Type: cross Abstract: Multimodal supervised learning seeks to leverage multiple heterogeneous data sources to improve predictive performance.
arXiv:2503. 22939v4 Announce Type: replace Abstract: The integration of heterogeneous multi-omics datasets at a systems level remains a central challenge for developing analytical and computational models in precision cancer diagnostics.
arXiv:2606. 14608v1 Announce Type: cross Abstract: Survival prediction plays a central role for healthcare providers and clinical researchers.
The paper introduces Coupled Tensor‑Tensor Completion (CTTC), a new framework that incorporates side information in tensor form to enhance tensor completion tasks. CTTC leverages hidden connections among multimodal tensors and is grounded in distance metric learning and group theory. Experiments on the DTD and LINCS datasets show that CTTC outperforms existing methods such as HaLRTC, CTRC, Cell, and NTDDR in both runtime and root‑sum‑of‑squares error for drug effect prediction.
arXiv:2608. 13939v1 Announce Type: cross Abstract: Ultrasound is the primary imaging modality for assessing thyroid nodules, and the ACR TI-RADS framework standardizes diagnosis through five ultrasound feature categories that are aggregated into five risk levels (TR1-TR5).
arXiv:2607. 27289v1 Announce Type: new Abstract: The promise of multimodal fusion lies in combining complementary sources of evidence, yet more evidence does not always yield a better prediction.
arXiv:2609.25088v1 Announce Type: cross Abstract: Survival prediction for glioblastoma multiforme (GBM) demands models that are both accurate and interpretable, yet existing approaches treat these ob...