The paper introduces DeToxR, a reinforcement‑learning‑enhanced large language model designed to support decision making in acute toxicology cases. It fuses unstructured narratives from paramedics and patients with structured vital‑sign data to predict co‑ingested substances across 14 classes. In preliminary validation, DeToxR outperforms baseline models, achieving higher micro‑F1 and recall scores for poison identification.
By Nico Oberl\"ander, David Bani-Harouni, Tobias Zellner, Nassir Navab, Florian Eyer, Matthias Keicher
CARE: Causally-Aligned Reasoning Exploration for Medical Large Language Models proposes a new framework to improve medical reasoning in LLMs. It introduces two key conditions—Causal Sufficiency and Proximal Learnability—to curate high-quality training trajectories, using agreement-based self-verification and dynamic entropy bounds. Experiments on medical multimodal and text-only benchmarks show that CARE outperforms competitors, reducing incorrect reasoning and enhancing training stability.
By Yucheng Zhou, Peng Luo, Qianning Wang, Chengzhong Xu, Jianbing Shen
The paper proposes a reinforcement learning (RL) fine‑tuning framework for electronic health record (EHR) foundation models, treating them as generative policies over patient trajectories. By framing clinical prediction tasks such as hospital readmission as event‑conditioned, time‑windowed reasoning problems and designing time‑aware, rollout‑sensitive rewards, the authors show that RL fine‑tuning consistently outperforms pre‑trained backbones and strong baselines. The approach enables smaller models to surpass larger pre‑trained models in data‑limited settings, induces positive transfer across tasks, and produces trajectories with stronger structural and semantic alignment to ground truth, improving downstream utility.
By Yuxin Xiao, Sheng Zhang, Chandan Singh, Tristan Naumann, Hoifung Poon, Jianfeng Gao, Xiaodong Liu
arXiv:2601. 03321v3 Announce Type: replace-cross Abstract: Multimodal Large Language Models (MLLMs) have substantially advanced Radiology Report Generation (RRG), yet aligning them through reinforcement learning (RL) remains challenging due to heterogeneous medical supervision.
By Kun Zhao, Guodong Liu, Hui Ji, Siyuan Dai, Pan Wang, Jifeng Song, Chenghua Lin, Liang Zhan, Haoteng Tang
arXiv:2607. 12687v1 Announce Type: cross Abstract: LLMs can perform language-based quantitative prediction from unstructured inputs, but remain susceptible to hallucinations and overconfident errors, making it critical to know not only what a model predicts, but when its predictions can be trusted.
By Mehak Dhaliwal, Rasta Tadayon, Andong Hua, Haewon Jeong, Yao Qin
arXiv:2609.24480v1 Announce Type: cross
Abstract: Deploying Large Language Models (LLMs) in healthcare requires robust performance across two complementary dimensions - diagnostic reasoning: the conv...
By Kalash Shah, Kunal Singh, Snehan J, Shreyas Singh
The paper introduces POISE, a reinforcement learning algorithm that uses a model’s internal states as a value estimator to reduce variance in reinforcement learning with verifiable rewards (RLVR). By employing a lightweight probe that reads internal signals during the forward pass, POISE predicts baselines online and uses a cross‑rollout construction to keep gradients unbiased. Experiments on Qwen3‑4B and OLMo3‑7B‑Instruct‑DPO across six domains show POISE outperforms existing RLVR baselines, offering more stable training and a value model that generalizes across tasks and scales with the policy.
By Yunho Choi, Jongwon Lim, Woojin Ahn, Minjae Oh, Jeonghoon Shim, Yohan Jo
arXiv:2606. 08088v1 Announce Type: new Abstract: Reinforcement Learning from Verifiable Rewards (RLVR) has recently become a key paradigm for improving the reasoning abilities of Large Language Models (LLMs), yet it remains limited by sparse binary rewards and its ignorance of model-internal uncertainty.
By Qing Miao, Yiming Zhao, Jing Yang, Chenxi Liu, Yuehai Chen, Yuewen Liu, Shaoyi Du, Badong Chen
arXiv:2606. 01281v1 Announce Type: cross Abstract: Reinforcement learning with verifiable rewards (RLVR) has emerged as a powerful paradigm for enhancing the reasoning capabilities of large language models (LLMs).
By Yixiu Mao, Yun Qu, Qi Wang, Heming Zou, Xiangyang Ji
arXiv:2606. 08815v1 Announce Type: new Abstract: Reinforcement learning with verifiable rewards (RLVR) has emerged as a powerful paradigm for eliciting long-chain reasoning in large language models.
By Hao Chen, Zhanming Shen, Liyao Li, Yanyu Chen, Xuhang Zhu, Xiaomeng Hu, Qi Zhang, Ru Peng, Xiaoyu Shen, Haobo Wang, Junbo Zhao
arXiv:2606. 15866v1 Announce Type: new Abstract: Reinforcement Learning with Verifiable Rewards (RLVR) has become an effective post-training paradigm for improving the reasoning abilities of large language models.
By Qinjian Zhao, Zhihao Dou, Dinggen Zhang, Xiangyu Li, Chaoda Song, Zhongwei Wan, Xinpeng Li, Yanyan Zhang, Kaijie Chen, Qingtao Pan, Chengcheng Feng, Zhiqiang Gao, Xiaoyu Xia
arXiv:2609.37119v1 Announce Type: cross
Abstract: Recent approaches to reinforcement learning (RL) post-training for large language models increasingly remove the critic to reduce training instabilit...
By Hongyang Li, Xiao Li, Caesar Wu, Said Mammar, Gr\'egoire Danoy, Pascal Bouvry