arXiv Computer Vision

CARD: Calibration via Agreement in Reverse Diffusion for Out-of-Domain MRI Segmentation

arXiv Computer Vision
Aug 27

Reliability analysis for BraTS-GoAT segmentation: a controlled robustness study of deep-ensemble uncertainty

The study evaluates the reliability of deep‑ensemble uncertainty for brain tumour segmentation on the BraTS‑GoAT dataset. A 5‑fold cross‑validated nnU‑Net baseline and a 3‑seed deep ensemble were compared for calibration and error detection; the ensemble showed modest gains in calibration on in‑distribution data but the single model’s confidence remained flat while accuracy degraded under synthetic corruptions. Disagreement among ensemble members rose sharply with corruption severity, proving to be a more sensitive indicator of acquisition shift than single‑model confidence.

By Riya Deepak Shet, Chenxi Liang, Le Zhang
arXiv AI
Oct 9

Missing Modality-Aware Calibration for Trustworthy Brain Tumor Segmentation

The paper introduces Missing Modality-Aware Local Temperature Scaling (MMA‑LTS), a post‑hoc voxel‑wise confidence calibration technique designed for multimodal brain tumor segmentation. MMA‑LTS adapts a temperature field based on which MRI modalities are present and a voxel‑wise difficulty score, addressing calibration errors that arise when specific modalities are missing. Experiments on BraTS 2020 and FeTS 2024 demonstrate that MMA‑LTS improves calibration while maintaining segmentation accuracy across various missing‑modality scenarios.

By Sol Lee, Hyunji Kim, Sungrae Hong, Donghee Han, Mun Yi
arXiv Machine Learning
Jul 28

Trustworthy Medical Segmentation: Uncertainty-Aware U-Net Evaluation Under Clinical Image Degradation

arXiv:2607. 22727v1 Announce Type: cross Abstract: Medical image segmentation models often report high benchmark accuracy under ideal imaging conditions, yet their failures under clinical degradation can be quiet: sensor noise, patient motion, low- resolution acquisition, and contrast variability may all alter model behavior without producing an obvious warning.

By Pranav Kaliaperumal, Manisha Kaliaperumal
arXiv Machine Learning
Oct 15

Contrastive uncertainty learning for robust multi-structure segmentation in lower-pelvic MR

The paper introduces Contrastive Uncertainty Learning (CUL), a supervised framework that leverages voxel‑wise predictive uncertainty to guide representation learning for multi‑structure segmentation in lower‑pelvic MRI. Using Monte Carlo Dropout, CUL identifies uncertain voxels and shapes the embedding space so that low‑uncertainty, correctly predicted features become stable while high‑uncertainty or misclassified features are repelled, preventing feature collapse at challenging boundaries. Evaluated on 589 prostate MRI scans with a ViT‑based UperNet decoder, CUL achieves comparable Dice scores to a baseline while significantly reducing surface distance for most structures, and ablation studies confirm the necessity of both uncertainty‑guided sampling and the contrastive objective.

By Bilal Sidiqi, Yipei Wang, Wen Yan, Shaheer U. Saeed, Daniel C. Alexander, Yipeng Hu
arXiv Computer Vision
Sep 24

Recursive Uncertainty-Gated Image Registration for Learning-based Algorithms

The paper introduces Recursive Uncertainty-Gated Image Registration (RUGI), an iterative refinement method that updates deformation fields predicted by learning-based registration models using a gating map. Two gating strategies are explored: an uncertainty-based approach and an image residual error approach, both concentrating updates on difficult regions. Experiments on cardiac MRI and echocardiography datasets show that RUGI consistently improves registration accuracy, with the error-gated variant reducing MSE by 27‑37% on pretrained models and lowering ejection fraction estimation errors.

By Clara Rodrigo Gonz\'alez, Oscar Bates, Fu Siong Ng, Meng-Xing Tang
arXiv AI
Oct 15

Generalizable field of view extension for diffusion MRI via conditional flow matching

arXiv:2610.17401v1 Announce Type: new Abstract: Incomplete field-of-view (FOV) diffusion MRI (dMRI) acquisitions compromise whole-brain white matter analysis by excluding brain regions from tractogra...

By Gaurav Rudravaram, Lianrui Zuo, Ema Topolnjak, Michael E. Kim, Adam M. Saunders, Elyssa M. McMaster, Paula Trujillo, Ely E. Wesley, Colin D. McKnight, Pratik P. Pandharipande, Mayur B. Patel, Cayce Strength, Brenda T. Pund, Amelia W Maiga, Robert S. Dittus, David A. Bennett, Julie A. Schneider, Konstantinos Arfanakis, The HABS-HD Study Team, Derek B. Archer, Timothy J. Hohman, Yelena Bodien, Daniel C. Moyer, Kurt G. Schilling, Bennett A. Landman
arXiv AI
Jun 2

CardioLens: Revealing the Clinical Reality Gap of MLLMs via Multi-Sequence Cardiac MRI Evaluations

arXiv:2606. 00123v1 Announce Type: cross Abstract: Multimodal Large Language Models (MLLMs) have shown strong performance on public medical benchmarks, yet existing evaluations often remain weak proxies for clinical use, relying on isolated inputs and simplified recognition-style tasks.

By Zixian Su, Hongkai Zhang, Fan Gao, Encheng Su, Taiping Qu, Jingwei Guo, Nan Zhang, Hui Wang, Zhen Zhou, Kairui Bo, Yan Chen, Yue Ren, Shuai Li, Lei Xu, Henggui Zhang